CD3 epsilon recombinant antibody
Anti-CD3 epsilon [145-2C11]
Reactivity
Mouse
Applications
Flow Cytometry, Functional Assay, Western Blot, Immunoprecipitation
Purity
Protein A Affinity Purified
Synonyms
CD3 epsilon; Anti-CD3 epsilon [145-2C11]; T-cell surface glycoprotein CD3 epsilon chain; T-cell surface antigen T3/Leu-4 epsilon chain CD_antigen; CD3e; CD3 epsilon recombinant antibody
Reactivity
Mouse
Isotype
Rabbit IgG, kappa
Clone Number
145-2C11
Specificity
Recognizes a 25-kDa protein component (CD3e, originally called T3-e) of the antigen-specific T-cell receptor.
Purity/Purification
Protein A Affinity Purified
Sequence Length
202
Applicable Applications for CD3 epsilon recombinant antibody
Flow Cytometry (FC/FACS), Western Blot (WB), Immunoprecipitation (IP), Activation
Buffer Composition
PBS only with 0.02% Proclin 300.
Immunogen
H-2Kb-specific murine cytotoxic T-lymphocyte (CTL) clone.
Chimeric Use Statement
This chimeric rabbit antibody was made using the variable domain sequences of the original Hamster IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Preparation and Storage
Store at 4 degree C for up to 3 months. For longer storage, aliquot and store at -20 degree C.
Related Product Information for CD3 epsilon recombinant antibody
Recombinant monoclonal antibody to CD3 epsilon. Manufactured using a Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 145-2C11. This chimeric rabbit antibody was made using the variable domain sequences of the original Hamster IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Product Categories/Family for CD3 epsilon recombinant antibody
References
Leo O, Foo M, Sachs DH, Samelson LE, Bluestone JA. Identification of a monoclonal antibody specific for a murine T3 polypeptide. Proc Natl Acad Sci U S A. 1987 Mar; 84(5):1374-8. PMID:2950524
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
22,642 Da
NCBI Official Full Name
CD3 epsilon
NCBI Official Symbol
CD3E
NCBI Protein Information
T-cell surface glycoprotein CD3 epsilon chain
UniProt Protein Name
T-cell surface glycoprotein CD3 epsilon chain
UniProt Gene Name
CD3E
UniProt Entry Name
CD3E_CANLF
Uniprot Description
The CD3 complex mediates signal transduction, resulting in T-cell activation and proliferation. Required for normal immune responses.
Research Articles on CD3 epsilon
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Product Notes
The CD3 epsilon cd3e (Catalog #AAA488070) is a Recombinant Antibody and is intended for research purposes only. The product is available for immediate purchase. The Anti-CD3 epsilon [145-2C11] reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CD3 epsilon can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Western Blot (WB), Immunoprecipitation (IP), Activation. Researchers should empirically determine the suitability of the CD3 epsilon cd3e for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD3 epsilon, Recombinant Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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