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Western Blot (WB) (Figure 1: Western blot analysis using MYOD1 mAb against HEK293 (1) and MYOD1-hIgGFc transfected HEK293 (2) cell lysate.)

Mouse anti-Human MYOD1 Antibody | anti-MYOD1 antibody

MYOD1 Antibody

Reactivity
Human
Applications
Western Blot, ELISA
Synonyms
MYOD1; MYOD1 Antibody; PUM; MYF3; MYOD; bHLHc1; anti-MYOD1 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Isotype
IgG1
Clone Number
1C8
Form/Format
Ascitic fluid containing 0.03% sodium azide.
Sequence Length
2058
Applicable Applications for anti-MYOD1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500-1:2000
ELISA: 1:10000
Immunogen
Purified recombinant fragment of human MYOD1 expressed in E. Coli.
Preparation and Storage
Store at 4 degree C, for long term storage, store at-20 degree C.

Western Blot (WB)

(Figure 1: Western blot analysis using MYOD1 mAb against HEK293 (1) and MYOD1-hIgGFc transfected HEK293 (2) cell lysate.)

Western Blot (WB) (Figure 1: Western blot analysis using MYOD1 mAb against HEK293 (1) and MYOD1-hIgGFc transfected HEK293 (2) cell lysate.)
Related Product Information for anti-MYOD1 antibody
This gene encodes a nuclear protein that belongs to the basic helix-loop-helix family of transcription factors and the myogenic factors subfamily. It regulates muscle cell differentiation by inducing cell cycle arrest, a prerequisite for myogenic initiation. The protein is also involved in muscle regeneration. It activates its own transcription which may stabilize commitment to myogenesis.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
34kDa
NCBI Official Full Name
unconventional myosin-X
NCBI Official Synonym Full Names
myosin X
NCBI Official Symbol
MYO10
NCBI Protein Information
unconventional myosin-X
UniProt Protein Name
Unconventional myosin-X
UniProt Gene Name
MYO10
UniProt Synonym Gene Names
KIAA0799

NCBI Description

This gene encodes a member of the myosin superfamily. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-10 (MYH10). Unconventional myosins contain the basic domains of conventional myosins and are further distinguished from class members by their tail domains. This gene functions as an actin-based molecular motor and plays a role in integration of F-actin and microtubule cytoskeletons during meiosis. [provided by RefSeq, Dec 2011]

Uniprot Description

Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. MYO10 binds to actin filaments and actin bundles and functions as plus end-directed motor. The tail domain binds to membranous compartments containing phosphatidylinositol 3,4,5-trisphosphate or integrins, and mediates cargo transport along actin filaments. Regulates cell shape, cell spreading and cell adhesion. Stimulates the formation and elongation of filopodia. May play a role in neurite outgrowth and axon guidance. In hippocampal neurons it induces the formation of dendritic filopodia by trafficking the actin-remodeling protein VASP to the tips of filopodia, where it promotes actin elongation. Plays a role in formation of the podosome belt in osteoclasts.

Research Articles on MYOD1

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Product Notes

The MYOD1 myo10 (Catalog #AAA850471) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The MYOD1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MYOD1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500-1:2000 ELISA: 1:10000. Researchers should empirically determine the suitability of the MYOD1 myo10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MYOD1, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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