Western Blot (WB)
(Figure 1: Western blot analysis using MSI2 mouse mAb against NTERA-2 (1), SW620 (2) and T47D (3) cell lysate.)
Mouse anti-Human MSI2 Antibody | anti-MSI2 antibody
MSI2 Antibody
Gene Names
MSI2; MSI2H
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, ELISA
Synonyms
MSI2; MSI2 Antibody; MSI2H; MGC3245; FLJ36569; anti-MSI2 antibody
Host
Mouse
Reactivity
Human
Isotype
IgG1
Clone Number
2C11
Form/Format
Ascitic fluid containing 0.03% sodium azide.
Sequence Length
328
Applicable Applications for anti-MSI2 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
WB: 1:500-1:2000
IHC: 1:200-1:1000
ELISA: 1:10000
IHC: 1:200-1:1000
ELISA: 1:10000
Immunogen
Purified recombinant fragment of human MSI2 expressed in E. Coli.
Preparation and Storage
Store at 4 degree C, for long term storage, store at-20 degree C.
Western Blot (WB)
(Figure 1: Western blot analysis using MSI2 mouse mAb against NTERA-2 (1), SW620 (2) and T47D (3) cell lysate.)
Western Blot (WB)
(Figure 1: Western blot analysis using MSI2 mouse mAb against NTERA-2 (1), SW620 (2) and T47D (3) cell lysate.)
Immunohistochemistry (IHC)
(Figure 2: Immunohistochemical analysis of paraffin-embedded ovarian cancer (left) and cerebellum tissues (right) using MSI2 mouse mAb with DAB staining.)
Immunohistochemistry (IHC)
(Figure 2: Immunohistochemical analysis of paraffin-embedded ovarian cancer (left) and cerebellum tissues (right) using MSI2 mouse mAb with DAB staining.)
Testing Data
Testing Data
Related Product Information for anti-MSI2 antibody
Msi2 (musashi homolog 2), also known as MSI2H, is a 328 amino acid protein that localizes to the cytoplasm and contains two RRM (RNA recognition motif) domains. Expressed ubiquitously at low levels, Msi2 functions as an RNA binding protein that, by regulating the expression of target mRNAs, is thought to play a role in the proliferation and maintenance of stem cells within the central nervous system. Msi2 is subject to posttranslational phosphorylation and is upregulated in response to brain injury, suggesting a role in healing and brain tissue regeneration. Chromosomal aberrations involving the Msi2 gene are associated with the progression of chronic myeloid leukemia. Multiple isoforms of Msi2 exist due to alternative splicing events.Tissue specificity: Ubiquitous; detected at low levels.
Product Categories/Family for anti-MSI2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
35kDa
NCBI Official Full Name
RNA-binding protein Musashi homolog 2 isoform a
NCBI Official Synonym Full Names
musashi RNA binding protein 2
NCBI Official Symbol
MSI2
NCBI Official Synonym Symbols
MSI2H
NCBI Protein Information
RNA-binding protein Musashi homolog 2
UniProt Protein Name
RNA-binding protein Musashi homolog 2
Protein Family
UniProt Gene Name
MSI2
UniProt Synonym Gene Names
Musashi-2
NCBI Description
This gene encodes an RNA-binding protein that is a member of the Musashi protein family. The encoded protein is transcriptional regulator that targets genes involved in development and cell cycle regulation. Mutations in this gene are associated with poor prognosis in certain types of cancers. This gene has also been shown to be rearranged in certain cancer cells. [provided by RefSeq, Apr 2016]
Uniprot Description
RNA binding protein that regulates the expression of target mRNAs at the translation level. May play a role in the proliferation and maintenance of stem cells in the central nervous system ().
Research Articles on MSI2
Similar Products
Product Notes
The MSI2 msi2 (Catalog #AAA850304) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The MSI2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MSI2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA). WB: 1:500-1:2000 IHC: 1:200-1:1000 ELISA: 1:10000. Researchers should empirically determine the suitability of the MSI2 msi2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MSI2, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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