Western Blot (WB)
(Figure 1. Western blot analysis using CRTC1 mouse mAb against CRTC1-hIgGFc transfected HEK293 cell lysate)
Mouse anti-Human CRTC1 Antibody | anti-CRTC1 antibody
CRTC1 Antibody
IF: 1:200-1:1000
FC: 1:200-1:400
ELISA: 1:10000
Western Blot (WB)
(Figure 1. Western blot analysis using CRTC1 mouse mAb against CRTC1-hIgGFc transfected HEK293 cell lysate)
Western Blot (WB)
(Figure 1. Western blot analysis using CRTC1 mouse mAb against CRTC1-hIgGFc transfected HEK293 cell lysate)
Immunofluorescence (IF)
(Figure 2. Immunofluorescence analysis of U251 (left) and NTERA2 (right) cells using CRTC1 mAb (green). Red. Actin filaments have been labeled with DY-554 phalloidin. Blue. DRAQ5 fluorescent DNA dye.)
Immunofluorescence (IF)
(Figure 2. Immunofluorescence analysis of U251 (left) and NTERA2 (right) cells using CRTC1 mAb (green). Red. Actin filaments have been labeled with DY-554 phalloidin. Blue. DRAQ5 fluorescent DNA dye.)
Flow Cytometry (FC/FACS)
(Figure 3. Flow cytometric analysis of K562 cells using CRTC1 mouse mAb (green) and negative control (purple).)
Flow Cytometry (FC/FACS)
(Figure 3. Flow cytometric analysis of K562 cells using CRTC1 mouse mAb (green) and negative control (purple).)
NCBI and Uniprot Product Information
Uniprot Description
Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR). In the hippocampus, involved in late-phase long-term potentiation (L-LTP) maintenance at the Schaffer collateral-CA1 synapses. May be required for dendritic growth of developing cortical neurons (). In concert with SIK1, regulates the light-induced entrainment of the circadian clock. In response to light stimulus, coactivates the CREB-mediated transcription of PER1 which plays an important role in the photic entrainment of the circadian clock.
Research Articles on CRTC1
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Product Notes
The CRTC1 crtc1 (Catalog #AAA850612) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CRTC1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CRTC1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunofluorescence (IF), Flow Cytometry (FC/FACS), ELISA (EIA). WB: 1:500-1:2000 IF: 1:200-1:1000 FC: 1:200-1:400 ELISA: 1:10000. Researchers should empirically determine the suitability of the CRTC1 crtc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CRTC1, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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