Western Blot (WB)
(Western Blot: Sample: Recombinant FGb, Rat.)
Mouse anti-Rat Fibrinogen Beta Antibody | anti-FGb antibody
Monoclonal Antibody to Fibrinogen Beta (FGb)
Immunohistochemistry: 5-20ug/mL
Immunocytochemistry: 5-20ug/mL
Optimal working dilutions must be determined by end user.
Store at 4 degree C for frequent use.
Aliquot and store at -20 degree C for 24 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Western Blot (WB)
(Western Blot: Sample: Recombinant FGb, Rat.)
Western Blot (WB)
(Western Blot: Sample: Recombinant FGb, Rat.)
NCBI and Uniprot Product Information
NCBI Description
cleaved by thrombin; plays a role in wound healing [RGD, Feb 2006]
Uniprot Description
FGB: Fibrinogen has a double function: yielding monomers that polymerize into fibrin and acting as a cofactor in platelet aggregation. Defects in FGB are a cause of congenital afibrinogenemia (CAFBN). This rare autosomal recessive disorder is characterized by bleeding that varies from mild to severe and by complete absence or extremely low levels of plasma and platelet fibrinogen. Patients with congenital fibrinogen abnormalities can manifest different clinical pictures. Some cases are clinically silent, some show a tendency toward bleeding and some show a predisposition for thrombosis with or without bleeding.
Protein type: Adaptor/scaffold; Cell surface; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 2q34
Cellular Component: cell cortex; cell surface; cytoplasm; external side of plasma membrane; extracellular space; fibrinogen complex
Molecular Function: cell adhesion molecule binding; chaperone binding; protein binding, bridging; receptor binding; structural molecule activity
Biological Process: adaptive immune response; cell-matrix adhesion; cellular protein complex assembly; fibrinolysis; induction of bacterial agglutination; innate immune response; plasminogen activation; positive regulation of exocytosis; positive regulation of heterotypic cell-cell adhesion; positive regulation of protein secretion; positive regulation of vasoconstriction; protein polymerization; response to calcium ion; signal transduction
Research Articles on FGb
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Product Notes
The FGb fgb (Catalog #AAA2025757) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Monoclonal Antibody to Fibrinogen Beta (FGb) reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Fibrinogen Beta can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Immunoprecipitation (IP). Western blotting: 0.5-2ug/mL Immunohistochemistry: 5-20ug/mL Immunocytochemistry: 5-20ug/mL Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the FGb fgb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Fibrinogen Beta, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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