Mouse VCAN (Versican core protein) ELISA Kit | VCAN elisa kit
Mouse VCAN (Versican core protein) ELISA Kit
Inter-Assay: CV<10%
NCBI and Uniprot Product Information
Uniprot Description
CSPG2: May play a role in intercellular signaling and in connecting cells with the extracellular matrix. May take part in the regulation of cell motility, growth and differentiation. Binds hyaluronic acid. Defects in VCAN are the cause of Wagner syndrome type 1 (WGN1). WGN is a dominantly inherited vitreoretinopathy characterized by an optically empty vitreous cavity with fibrillary condensations and a preretinal avascular membrane. Other optical features include progressive chorioretinal atrophy, perivascular sheating, subcapsular cataract and myopia. Systemic manifestations are absent in WGN. Belongs to the aggrecan/versican proteoglycan family. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted, signal peptide; Secreted; Motility/polarity/chemotaxis; Cell adhesion
Cellular Component: extracellular matrix; proteinaceous extracellular matrix; extracellular space; cell surface; intracellular membrane-bound organelle; membrane; extracellular region
Molecular Function: extracellular matrix structural constituent; hyaluronic acid binding; calcium ion binding; carbohydrate binding; protein phosphatase binding
Biological Process: osteoblast differentiation; central nervous system development; heart development; regulation of phosphoprotein phosphatase activity; glial cell migration; cell adhesion; skeletal development
Research Articles on VCAN
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Product Notes
The Mouse VCAN vcan (Catalog #AAA7612724) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7612724 ELISA Kit recognizes Mouse VCAN. It is sometimes possible for the material contained within the vial of "VCAN (Versican core protein), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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