Typical Testing Data/Standard Curve (for reference only)
Mouse Protein-arginine deiminase type-2, PADI2 ELISA Kit | PADI2 elisa kit
Mouse Protein-arginine deiminase type-2, PADI2 ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Principle of the Assay: This kit is an Enzyme-Linked Immunosorbent Assay (ELISA). The plate has been pre-coated with Mouse PADI2 antibody. PADI2 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Mouse PADI2 Antibody is added and binds to PADI2 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated PADI2 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Mouse PADI2. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq, Jul 2008]
Uniprot Description
PADI2: Catalyzes the deimination of arginine residues of proteins. Belongs to the protein arginine deiminase family.
Protein type: EC 3.5.3.15; Hydrolase
Chromosomal Location of Human Ortholog: 1p36.13
Cellular Component: cytoplasm
Molecular Function: estrogen receptor binding; calcium ion binding; protein-arginine deiminase activity
Biological Process: substantia nigra development; estrogen receptor signaling pathway; chromatin-mediated maintenance of transcription; peptidyl-citrulline biosynthetic process from peptidyl-arginine
Research Articles on PADI2
Similar Products
Product Notes
The Mouse PADI2 padi2 (Catalog #AAA1605596) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA1605596 ELISA Kit recognizes Mouse PADI2. It is sometimes possible for the material contained within the vial of "Protein-arginine deiminase type-2, PADI2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
