Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Mouse Multimerin-1 (MMRN1) Standard Curve.)
Mouse Multimerin-1 (MMRN1) ELISA Kit | MMRN1 elisa kit
Mouse Multimerin-1 (MMRN1) ELISA Kit
Gene Names
Mmrn1; Mmrn; Emilin4; 4921530G03Rik
Reactivity
Mouse
Synonyms
Multimerin-1 (MMRN1); Mouse Multimerin-1 (MMRN1) ELISA Kit; MMRN1; ECM; EMILIN4; GPIa*; MMRN; OTTHUMP00000161558; glycoprotein Ia*; MMRN1 elisa kit
Reactivity
Mouse
Specificity
Mouse Multimerin-1 (MMRN1) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse MMRN1. No significant cross-reactivity or interference between Mouse MMRN1 and analogues was observed.
Sequence Length
1209
Assay Type
Sandwich ELISA (Quantitative)
Samples
Cell Culture Supernatants, Serum, Plasma, Other Biological Fluids
Detection Method
Colorimetric
Usage Notes
* Do not mix components from different kit lots or use reagents beyond the kit expiration date.
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Preparation and Storage
Store at 2-8 degree C.
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Mouse Multimerin-1 (MMRN1) Standard Curve.)
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Mouse Multimerin-1 (MMRN1) Standard Curve.)
Related Product Information for MMRN1 elisa kit
Description: This Mouse Multimerin-1 (MMRN1) ELISA Kit employs a two-site sandwich ELISA to quantitate MMRN1 in samples. An antibody specific for MMRN1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any MMRN1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for MMRN1 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of MMRN1 bound in the initial step. The color development is stopped and the intensity of the color is measured.
Background: Multimerin is a massive, soluble protein found in platelets and in the endothelium of blood vessels. It is comprised of subunits linked by interchain disulfide bonds to form large, variably sized homomultimers. Multimerin is a factor V/Va-binding protein and may function as a carrier protein for platelet factor V. It may also have functions as an extracellular matrix or adhesive protein. Recently, patients with an unusual autosomal-dominant bleeding disorder (factor V Quebec) were found to have a deficiency of platelet multimerin.
Background: Multimerin is a massive, soluble protein found in platelets and in the endothelium of blood vessels. It is comprised of subunits linked by interchain disulfide bonds to form large, variably sized homomultimers. Multimerin is a factor V/Va-binding protein and may function as a carrier protein for platelet factor V. It may also have functions as an extracellular matrix or adhesive protein. Recently, patients with an unusual autosomal-dominant bleeding disorder (factor V Quebec) were found to have a deficiency of platelet multimerin.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
multimerin-1 isoform b
NCBI Official Synonym Full Names
multimerin 1
NCBI Official Symbol
Mmrn1
NCBI Official Synonym Symbols
Mmrn; Emilin4; 4921530G03Rik
NCBI Protein Information
multimerin-1
UniProt Protein Name
Multimerin-1
Protein Family
UniProt Gene Name
Mmrn1
UniProt Entry Name
MMRN1_MOUSE
Uniprot Description
MMRN1: Carrier protein for platelet (but not plasma) factor V/Va. Plays a role in the storage and stabilization of factor V in platelets. Upon release following platelet activation, may limit platelet and plasma factor Va-dependent thrombin generation. Ligand for integrin alpha-IIb/beta-3 and integrin alpha-V/beta-3 on activated platelets, and may function as an extracellular matrix or adhesive protein. Deficiency in multimerin-1 due to proteolytic degradation within the platelet alpha granules is associated with an autosomal dominant bleeding disorder (factor V Quebec). 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Secreted, signal peptide
Cellular Component: extracellular region
Research Articles on MMRN1
Similar Products
Product Notes
The Mouse MMRN1 mmrn1 (Catalog #AAA9717603) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9717603 ELISA Kit recognizes Mouse MMRN1. It is sometimes possible for the material contained within the vial of "Multimerin-1 (MMRN1), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
