Mouse Kallikrein 1 (KLK1) ELISA Kit | KLK1 elisa kit
Mouse Kallikrein 1 (KLK1) Mini Samples ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the kallikrein subfamily of serine proteases that are involved in diverse physiological functions such as skin desquamation, tooth enamel formation, seminal liquefaction, synaptic neural plasticity and brain function. The encoded preproprotein undergoes proteolytic cleavage of the activation peptide to generate the functional enzyme. Mice lacking the encoded protein are unable to generate significant levels of kinins in most tissues, develop cardiovascular abnormalities and exhibit hypercalciuria of renal origin. This gene is located in a cluster of several related kallikrein genes on chromosome 7. Alternative splicing results in multiple transcript variants encoding different isoforms, some of which may undergo similar processing. [provided by RefSeq, Feb 2016]
Uniprot Description
KLK1: Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. Belongs to the peptidase S1 family. Kallikrein subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.4.21.35; Protease
Chromosomal Location of Human Ortholog: 7 B3|7 28.74 cM
Cellular Component: extracellular space; nucleus; protein complex
Molecular Function: endopeptidase activity; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; serine-type endopeptidase activity
Research Articles on KLK1
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Product Notes
The Mouse KLK1 klk1 (Catalog #AAA2087727) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2087727 ELISA Kit recognizes Mouse KLK1. It is sometimes possible for the material contained within the vial of "Kallikrein 1 (KLK1), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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