Mouse Histone Deacetylase 6 ELISA Kit | Hdac6 elisa kit

Mouse Histone Deacetylase 6 ELISA Kit

Cat. Num. AAA3807207

• Gene Names: Hdac6; Hd6; Sfc6; Hdac5; mHDA2
• Reactivity: Mouse
• Synonyms: Histone Deacetylase 6; Mouse Histone Deacetylase 6 ELISA Kit; Hdac6 elisa kit

• Reactivity: Mouse
• Sequence Length: 1149

• Samples: Serum, plasma, cell culture supernate and other biological fluids
• Assay Type: Sandwich
• Detection Range: 0.5ng/ml-8ng/ml
• Sensitivity: 0.1 ng/ml

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for Hdac6 elisa kit

Intended Use: The Stop Solution changes the color from blue to yellow and the intensity of the color is measured at 450 nm using a spectrophotometer. In order to measure the concentrationofHISTONE DEACETYLASE 6in the sample, This HISTONE DEACETYLASE 6ELISA Kit includes a set of calibration standards. The calibration standards are assayed at the same time as the samples and allow the operator to produce a standard curve of Optical Density versusHISTONE DEACETYLASE 6concentration. The concentration ofHISTONE DEACETYLASE 6in the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 341941079
• NCBI GeneID: 15185
• UniProt Accession #: Q9Z2V5
• NCBI Official Full Name: Histone deacetylase 6
• NCBI Official Synonym Full Names: histone deacetylase 6
• NCBI Official Symbol: Hdac6
• NCBI Official Synonym Symbols: Hd6; Sfc6; Hdac5; mHDA2
• NCBI Protein Information: histone deacetylase 6
• UniProt Protein Name: Histone deacetylase 6
• Protein Family: Histone deacetylase
• UniProt Gene Name: Hdac6
• UniProt Synonym Gene Names: HD6
• UniProt Entry Name: HDAC6_MOUSE

Uniprot Description

HDAC6: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin. Interacts with CBFA2T3, HDAC11 and SIRT2. Interacts with F-actin. Interacts with BBIP10. Under proteasome impairment conditions, interacts with UBD via its histone deacetylase 1 and UBP-type zinc-finger regions. Interacts with CYLD. Interacts with ZMYND15. Belongs to the histone deacetylase family. HD type 2 subfamily.

Protein type: Nuclear receptor co-regulator; Deacetylase; Ubiquitin conjugating system; EC 3.5.1.98

Cellular Component: axon; caveola; cell projection; centrosome; cytoplasm; cytoplasmic microtubule; cytosol; dendrite; dynein complex; histone deacetylase complex; inclusion body; leading edge; microtubule; microtubule associated complex; neuron projection; nucleus; perikaryon; perinuclear region of cytoplasm; protein complex

Molecular Function: actin binding; alpha-tubulin binding; beta-catenin binding; beta-tubulin binding; histone deacetylase activity; histone deacetylase binding; Hsp90 protein binding; hydrolase activity; metal ion binding; microtubule binding; misfolded protein binding; NAD-dependent histone deacetylase activity (H3-K14 specific); polyubiquitin binding; protein binding; tau protein binding; tubulin deacetylase activity; ubiquitin binding; ubiquitin protein ligase binding; zinc ion binding

Biological Process: chromatin modification; collateral sprouting; histone deacetylation; intracellular protein transport; lysosome localization; macroautophagy; misfolded or incompletely synthesized protein catabolic process; mitochondrion localization; negative regulation of microtubule depolymerization; negative regulation of protein complex disassembly; negative regulation of proteolysis; positive regulation of signal transduction; protein amino acid deacetylation; protein complex disassembly; protein polyubiquitination; regulation of fat cell differentiation; regulation of gene expression, epigenetic; regulation of protein stability; regulation of receptor activity; regulation of transcription, DNA-dependent; response to misfolded protein; response to organic substance; response to toxin; transcription, DNA-dependent; ubiquitin-dependent protein catabolic process; ubiquitin-dependent protein catabolic process via the multivesicular body pathway