Mouse Heme Carrier Protein 1 ELISA Kit | SLC46A1 elisa kit

Mouse Heme Carrier Protein 1 ELISA Kit

Cat. Num. AAA3807047

• Gene Names: SLC46A1; G21; HCP1; PCFT
• Reactivity: Mouse
• Synonyms: Heme Carrier Protein 1; Mouse Heme Carrier Protein 1 ELISA Kit; SLC46A1 elisa kit

• Reactivity: Mouse
• Sequence Length: 459

• Samples: Serum, plasma, cell culture supernate and other biological fluids
• Assay Type: Sandwich
• Detection Range: 1.25ng/ml-20ng/ml
• Sensitivity: 0.1 ng/ml

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for SLC46A1 elisa kit

Intended Use: The Stop Solution changes the color from blue to yellow and the intensity of the color is measured at 450 nm using a spectrophotometer. In order to measure the concentration ofHEME CARRIER PROTEIN 1in the sample, This HEME CARRIER PROTEIN 1ELISA Kit includes a set of calibration standards. The calibration standards are assayed at the same time as the samples and allow the operator to produce a standard curve of Optical Density versusHEME CARRIER PROTEIN 1concentration. The concentration ofHEME CARRIER PROTEIN 1in the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 94717633
• NCBI GeneID: 113235
• NCBI Official Full Name: heme carrier protein 1
• NCBI Official Synonym Full Names: solute carrier family 46 member 1
• NCBI Official Symbol: SLC46A1
• NCBI Official Synonym Symbols: G21; HCP1; PCFT
• NCBI Protein Information: proton-coupled folate transporter
• Protein Family: Proton-coupled folate transporter

NCBI Description

This gene encodes a transmembrane proton-coupled folate transporter protein that facilitates the movement of folate and antifolate substrates across cell membranes, optimally in acidic pH environments. This protein is also expressed in the brain and choroid plexus where it transports folates into the central nervous system. This protein further functions as a heme transporter in duodenal enterocytes, and potentially in other tissues like liver and kidney. Its localization to the apical membrane or cytoplasm of intestinal cells is modulated by dietary iron levels. Mutations in this gene are associated with autosomal recessive hereditary folate malabsorption disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2013]