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Typical Testing Data/Standard Curve (for reference only) (Mouse GAS6 PicoKine ELISA Kit standard curve )

Mouse GAS6 ELISA Kit | GAS6 elisa kit

Mouse GAS6 PicoKine ELISA Kit

Gene Names
Gas6; Gas-6
Reactivity
Mouse
Synonyms
GAS6; Mouse GAS6 PicoKine ELISA Kit; Growth arrest-specific protein 6; growth arrest-specific 6; AXL receptor tyrosine kinase ligand; AXL stimulatory factor; AXLLG; AXSF; growth arrest specific 6; growth arrest-specific protein 6; GAS6 elisa kit
Ordering
For Research Use Only!
Reactivity
Mouse
Specificity
Natural and recombinant mouse GAS6
Sequence Length
674
Samples
Cell culture supernates, serum and plasma (heparin, EDTA)
Assay Type
Sandwich
Detection Range
31.2pg/ml-2000pg/ml
Sensitivity
< 10pg/ml
Intra-assay Precision
Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision.
Inter-assay Precision
Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision.
Preparation and Storage
Store at 4 degree C for 6 months, at -20 degree C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)

Typical Testing Data/Standard Curve (for reference only)

(Mouse GAS6 PicoKine ELISA Kit standard curve )

Typical Testing Data/Standard Curve (for reference only) (Mouse GAS6 PicoKine ELISA Kit standard curve )
Related Product Information for GAS6 elisa kit
Principle of the assay: mouse GAS6 ELISA Kit was based on standard sandwich enzyme-linked immune-sorbent assay technology. A monoclonal antibody from rat specific for GAS6 has been precoated onto 96-well plates. Standards(NSO, D115-P673) and test samples are added to the wells, a biotinylated detection polyclonal antibody from goat specific for GAS6 is added subsequently and then followed by washing with PBS or TBS buffer. Avidin-Biotin-Peroxidase Complex was added and unbound conjugates were washed away with PBS or TBS buffer. HRP substrate TMB was used to visualize HRP enzymatic reaction. TMB was catalyzed by HRP to produce a blue color product that changed into yellow after adding acidic stop solution. The density of yellow is proportional to the mouse GAS6 amount of sample captured in plate.
Background: GAS6 (Growth arrest-specific 6), also known as AXLLG or AXSF, is a human gene coding for the Gas6 protein. It is mapped to 13q34. GAS6 was originally found as a gene upregulated by growth arrested fibroblasts. This gene product is a gamma-carboxyglutamic acid (Gla)-containing protein which thought to be involved in the stimulation of cell proliferation, and may play a role in thrombosis. What's more, the product of the GAS6 gene, a ligand for the AXL, MER, and TYRO3 tyrosine kinase receptors, is a vitamin K-dependent protein, structurally related to anticoagulant protein S but lacking its anticoagulant activity. This protein also shows great importance in the cardiovascular system.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
74,610 Da
NCBI Official Full Name
Growth arrest-specific protein 6
NCBI Official Synonym Full Names
growth arrest specific 6
NCBI Official Symbol
Gas6
NCBI Official Synonym Symbols
Gas-6
NCBI Protein Information
growth arrest-specific protein 6; GAS 6; AXL receptor tyrosine kinase ligand
UniProt Protein Name
Growth arrest-specific protein 6
UniProt Gene Name
Gas6
UniProt Synonym Gene Names
GAS-6
UniProt Entry Name
GAS6_MOUSE

Uniprot Description

Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.

Research Articles on GAS6

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Product Notes

The Mouse GAS6 gas6 (Catalog #AAA177239) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA177239 ELISA Kit recognizes Mouse GAS6. It is sometimes possible for the material contained within the vial of "GAS6, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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