Mouse Choline kinase alpha (CHKA) ELISA Kit | CHKA elisa kit
Mouse Choline kinase alpha (CHKA) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
The major pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway. The protein encoded by this gene is the initial enzyme in the sequence and may play a regulatory role. The encoded protein also catalyzes the phosphorylation of ethanolamine. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
CHKA: Has a key role in phospholipid biosynthesis and may contribute to tumor cell growth. Catalyzes the first step in phosphatidylcholine biosynthesis. Contributes to phosphatidylethanolamine biosynthesis. Phosphorylates choline and ethanolamine. Has higher activity with choline. Belongs to the choline/ethanolamine kinase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Kinase, other; Lipid Metabolism - glycerophospholipid; EC 2.7.1.82; EC 2.7.1.32
Chromosomal Location of Human Ortholog: 11q13.2
Cellular Component: cytosol
Molecular Function: choline binding; signal transducer activity; protein homodimerization activity; cholinesterase activity; drug binding; choline kinase activity; ethanolamine kinase activity; ATP binding
Biological Process: choline metabolic process; CDP-choline pathway; phospholipid metabolic process; glycerophospholipid biosynthetic process; phosphatidylethanolamine biosynthetic process; phosphatidylcholine biosynthetic process; lipid metabolic process; lipid transport; signal transduction; phosphorylation
Research Articles on CHKA
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Product Notes
The Mouse CHKA chka (Catalog #AAA7212128) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7212128 ELISA Kit recognizes Mouse CHKA. It is sometimes possible for the material contained within the vial of "Choline kinase alpha (CHKA), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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