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Mouse CD36 molecule (thrombospondin receptor) ELISA Kit | CD36 elisa kit

Mouse Platelet glycoprotein 4, CD36 ELISA Kit

Gene Names
Cd36; FAT; GPIV; Scarb3
Reactivity
Mouse
Synonyms
CD36 molecule (thrombospondin receptor); Mouse Platelet glycoprotein 4; CD36 ELISA Kit; Mouse Platelet glycoprotein 4 (CD36) ELISA kit; CHDS7; FAT; GP3B; GP4; GPIV; PASIV; SCARB3; CD36 antigen; CD36 antigen (collagen type I receptor; thrombospondin receptor) ; OTTHUMP00000207872; OTTHUMP00000207874; PAS-4 protein; cluster determinant 36; f; CD36 elisa kit
Ordering
For Research Use Only!
Reactivity
Mouse
Specificity
This assay has high sensitivity and excellent specificity for detection of Mouse CD36. No significant cross-reactivity or interference between Mouse CD36 and analogues was observed.
Sequence Length
472
Assay Type
Sandwich
Intra-assay Precision
Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.
Detection Wavelength
450 nm
Sample Volume
50-100ul
Protein Biological Process 1
Cell Adhesion
Protein Biological Process 3
Cell adhesion
Preparation and Storage
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
Related Product Information for CD36 elisa kit
Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for CD36 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any CD36 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for CD36 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of CD36 bound in the initial step. The color development is stopped and the intensity of the color is measured.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
52,698 Da
NCBI Official Full Name
platelet glycoprotein 4
NCBI Official Synonym Full Names
CD36 antigen
NCBI Official Symbol
Cd36
NCBI Official Synonym Symbols
FAT; GPIV; Scarb3
NCBI Protein Information
platelet glycoprotein 4; PAS-4; GPIIIB; PAS IV; glycoprotein IIIb; fatty acid translocase; platelet glycoprotein IV
UniProt Protein Name
Platelet glycoprotein 4
Protein Family
UniProt Gene Name
Cd36
UniProt Synonym Gene Names
GPIIIB; GPIV
UniProt Entry Name
CD36_MOUSE

Uniprot Description

CD36: Seems to have numerous potential physiological functions. Binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. May function as a cell adhesion molecule. Directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. Binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Receptor for thombospondins, THBS1 AND THBS2, mediating their antiangiogenic effects. Defects in CD36 are the cause of platelet glycoprotein IV deficiency (PG4D)[MIM:608404]; also known as CD36 deficiency. Platelet glycoprotein IV deficiency can be divided into 2 subgroups. The type I phenotype is characterized by platelets and monocytes/macrophages exhibiting complete CD36 deficiency. The type II phenotype lacks the surface expression of CD36 in platelets, but expression in monocytes/macrophages is near normal. Genetic variations in CD36 are associated with susceptibility to coronary heart disease type 7 (CHDS7). Belongs to the CD36 family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Cell adhesion

Cellular Component: Golgi apparatus; extracellular space; cell surface; protein complex; mitochondrion; intracellular membrane-bound organelle; endoplasmic reticulum; integral to membrane; caveola; lipid raft; membrane; apical part of cell; plasma membrane; intracellular; sarcolemma; external side of plasma membrane

Molecular Function: low-density lipoprotein receptor activity; protein binding; transforming growth factor beta binding; low-density lipoprotein binding; high-density lipoprotein binding; lipid binding

Biological Process: positive regulation of blood coagulation; positive regulation of interleukin-12 production; cGMP-mediated signaling; phagocytosis, recognition; negative regulation of transcription from RNA polymerase II promoter; pattern recognition receptor signaling pathway; negative regulation of transcription factor import into nucleus; fatty acid metabolic process; signal transduction; low density lipoprotein mediated signaling; sequestering of lipid; cell surface receptor linked signal transduction; positive regulation of MAPKKK cascade; transport; positive regulation of cell-matrix adhesion; regulation of transcription from RNA polymerase II promoter in response to oxidative stress; cell adhesion; long-chain fatty acid transport; receptor-mediated endocytosis; cholesterol transport; positive regulation of I-kappaB kinase/NF-kappaB cascade; negative regulation of systemic arterial blood pressure; positive regulation of interleukin-6 production; long-chain fatty acid metabolic process; positive regulation of tumor necrosis factor production; positive regulation of peptidyl-tyrosine phosphorylation; negative regulation of angiogenesis; defense response to Gram-positive bacterium; triacylglycerol metabolic process; response to mechanical stimulus; lipoprotein transport; fatty acid oxidation; positive regulation of phagocytosis, engulfment; nitric oxide mediated signal transduction; plasma membrane long-chain fatty acid transport; fatty acid transport; apoptotic cell clearance; positive regulation of cytokine secretion

Research Articles on CD36

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Product Notes

The Mouse CD36 cd36 (Catalog #AAA907949) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA907949 ELISA Kit recognizes Mouse CD36. It is sometimes possible for the material contained within the vial of "CD36 molecule (thrombospondin receptor), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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