Immunocytochemistry (ICC)
(Immunocytochemistry staining of acetone/methanol fixed bovine peripheral blood (lymphocyte-enriched suspension) using anti-bovine CD62L (IVA94); secondary antibody conjugated to FITC (green), DNA stained with DAPI (blue).)
Mouse anti-Cow, Human CD62L Antibody | anti-CD62L antibody
Anti-Bov CD62L Purified
Reactivity
Cow, Human
Applications
Flow Cytometry, Functional Assay, Immunoprecipitation, Immunocytochemistry
Purity
Purified by Protein-A Affinity Chromatography
Synonyms
CD62L; Anti-Bov CD62L Purified; selectin L; L-selectin; LSEL; SELL; LAM-1; LAM1; LECAM1; LEU8; LNHR; LYAM1; PLNHR; anti-CD62L antibody
Host
Mouse
Reactivity
Cow, Human
Isotype
IgG1
Clone Number
IVA94
Specificity
The antibody IVA94 reacts with an extracellular epitope of CD62L antigen (bovine). CD62L (L-selectin) is a 74-95 kDa single chain type I glycoprotein expressed on most peripheral blood B lymphocytes, T lymphocytes, monocytes and granulocytes; it is also present on a subset of NK cells and certain hematopoietic malignant cells.
Purity/Purification
Purified by Protein-A Affinity Chromatography
Form/Format
Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Concentration
1 mg/ml (varies by lot)
Sequence Length
370
Applicable Applications for anti-CD62L antibody
Flow Cytometry (FC/FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC)
Immunogen
Bovine leukocytes.
Preparation and Storage
Store at 2-8 degree C.
Immunocytochemistry (ICC)
(Immunocytochemistry staining of acetone/methanol fixed bovine peripheral blood (lymphocyte-enriched suspension) using anti-bovine CD62L (IVA94); secondary antibody conjugated to FITC (green), DNA stained with DAPI (blue).)
Immunocytochemistry (ICC)
(Immunocytochemistry staining of acetone/methanol fixed bovine peripheral blood (lymphocyte-enriched suspension) using anti-bovine CD62L (IVA94); secondary antibody conjugated to FITC (green), DNA stained with DAPI (blue).)
Related Product Information for anti-CD62L antibody
CD62L (L-selectin) is an adhesion glycoprotein that is constitutively expressed on the cell surface of leukocytes and mediates their homing to inflammatory sites and peripheral lymph nodes by enabling rolling along the venular wall. CD62L is also involved in activation-induced neutrophil aggregation. Activation-dependent CD62L shedding, however, counteracts neutrophil rolling. CD62L has also signaling roles including enhance of chemokine receptor expression. Similarly to CD62P, the major ligand of CD62L is PSGL-1 (P-selectin glycoprotein ligand-1).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
L-selectin
NCBI Official Symbol
SELL
NCBI Protein Information
L-selectin
UniProt Protein Name
L-selectin
UniProt Gene Name
SELL
UniProt Synonym Gene Names
LAM-1; LECAM1
UniProt Entry Name
LYAM1_BOVIN
Uniprot Description
Cell surface adhesion protein. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia ().
Research Articles on CD62L
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Product Notes
The CD62L sell (Catalog #AAA1800814) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-Bov CD62L Purified reacts with Cow, Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD62L can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC). Researchers should empirically determine the suitability of the CD62L sell for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD62L, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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