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Mouse anti-Human beta-hCG Antibody | anti-CGB antibody

Anti-beta-hCG Purified

Gene Names
CGB3; CGB; CGB5; CGB7; CGB8; hCGB
Reactivity
Human
Applications
Immunocytochemistry, ELISA
Purity
Purified by Protein-A Affinity Chromatography
Synonyms
beta-hCG; Anti-beta-hCG Purified; chorionic gonadotropin subunit beta; Chorionic gonadotropin beta; Choriogonadotropin beta; CG-beta; anti-CGB antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Isotype
IgG2b
Clone Number
HCG-61
Specificity
The antibody HCG-61 reacts with beta-subunit of human chorionic gonadotropin, a 40 kDa hormone. hCG belongs to the glycoprotein hormone family together with lutropin (LH), follitropin (FSH) and thyrotropin (TSH). hCG is synthesised by trophoblastic cells of the placenta during pregnancy and stimulates the growth of corpus luteum. The HCG-61 antibody reacts with association constant 5.1 x 10 10 l/mol. Following cross-reactivity (%) was determined by classic double-antibody RIA using unlabelled hormones: beta-hCG (77), alpha-hCG (1.3), hLH (0.86), hFSH (< 0.5), hTSH (< 0.5).
Purity/Purification
Purified by Protein-A Affinity Chromatography
Form/Format
Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Concentration
1 mg/ml (varies by lot)
Sequence Length
165
Applicable Applications for anti-CGB antibody
Immunocytochemistry (ICC), ELISA (EIA)
Immunogen
Human chorionic gonadotropin.
Preparation and Storage
Store at 2-8 degree C.
Related Product Information for anti-CGB antibody
hCG is a protein of the molecular weight about 40 kDa. hCG belongs to the glycoprotein hormone family together with lutropin (LH), follitropin (FSH) and thyrotropin (TSH). hCG is synthesised by trophoblastic cells of the placenta during pregnancy and stimulates the growth of corpus luteum. The other hormones are produced by anterior pituitary gland. All these hormones are structurally related being composed of two noncovalently associated subunits alpha and beta.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
NCBI Official Full Name
Choriogonadotropin subunit beta 3
NCBI Official Synonym Full Names
chorionic gonadotropin subunit beta 3
NCBI Official Symbol
CGB3
NCBI Official Synonym Symbols
CGB; CGB5; CGB7; CGB8; hCGB
NCBI Protein Information
choriogonadotropin subunit beta 3
UniProt Protein Name
Choriogonadotropin subunit beta 3
Protein Family
UniProt Gene Name
CGB3
UniProt Synonym Gene Names
CGB; CG-beta

NCBI Description

This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq, Jul 2008]

Uniprot Description

Beta subunit of the human chorionic gonadotropin (hCG). hCG is a complex glycoprotein composed of two glycosylated subunits alpha and beta which are non-covalently associated. The alpha subunit is identical to those in the pituitary gonadotropin hormones (LH, FSH and TSH). The beta subunits are distinct in each of the hormones and confer receptor and biological specificity. Has an essential role in pregnancy and maternal adaptation. Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy.

Research Articles on CGB

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Product Notes

The CGB cgb3 (Catalog #AAA1800686) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-beta-hCG Purified reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's beta-hCG can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), ELISA (EIA). Researchers should empirically determine the suitability of the CGB cgb3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "beta-hCG, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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