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Mouse Interleukin 18 Binding Protein (IL18BP) Antibody Pair Kit | IL18BP antibody pair kit

Mouse Interleukin 18 Binding Protein (IL18BP) Antibody Pair Kit (with Standard)

Gene Names
IL18BP; IL18BPa
Reactivity
Mouse
Applications
ELISA, ELISA
Synonyms
Interleukin 18 Binding Protein (IL18BP); Mouse Interleukin 18 Binding Protein (IL18BP) Antibody Pair Kit (with Standard); IL18BPa; MC51L-53L-54L Homolog Gene Product; Tadekinig-alfa; IL18BP antibody pair kit
Ordering
For Research Use Only!
Reactivity
Mouse
Applicable Applications for IL18BP antibody pair kit
ELISA (EIA), Chemiluminescence Immunoassays (CLIA), ELISPOT, Luminex
Samples
Serum, Plasma, Tissue Homogenates and Other Biological Fluids
Detection Range
125-8000pg/mL
Standard
Recombinant IL18BP (Lyophilized, 1 vial-10ug)
Capture Antibody
Rabbit polyclonal antibody (Liquid, 1 vial-400mug/800muL)
Detection Antibody
Biotinylated Rabbit polyclonal antibody (Liquid, 1 vial-100mug/500muL)
Producte Usage
Raw materials can be used for preparation of 5x96T or 10x96T ELISA Kits.
Antibody Support Pack
Antibody Support Pack (Buffer Pack) is sold separately as catalog #MBS2090685
Product Categories/Family for IL18BP antibody pair kit

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
17,478 Da
NCBI Official Full Name
Interleukin 18 binding protein
NCBI Official Synonym Full Names
interleukin 18 binding protein
NCBI Official Symbol
IL18BP
NCBI Official Synonym Symbols
IL18BPa
NCBI Protein Information
interleukin-18-binding protein
UniProt Protein Name
Interleukin-18-binding protein
UniProt Gene Name
IL18BP
UniProt Synonym Gene Names
IL-18BP

NCBI Description

The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]

Uniprot Description

Isoform A binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokine response.

Research Articles on IL18BP

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Product Notes

The Mouse IL18BP il18bp (Catalog #AAA2103924) is an Antibody Pair Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2103924 Antibody Pair Kit recognizes Mouse IL18BP. AAA Biotech's Interleukin 18 Binding Protein (IL18BP) can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Chemiluminescence Immunoassays (CLIA), ELISPOT, Luminex. Researchers should empirically determine the suitability of the IL18BP il18bp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Interleukin 18 Binding Protein (IL18BP), Antibody Pair Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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