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MIP3 alpha active protein

MIP3 alpha protein (Mouse)

Gene Names
Ccl20; CKb4; LARC; ST38; MIP3A; MIP-3A; Scya20; MIP-3[a]; exodus-1
Applications
User optimized
Purity
> 98% pure
Synonyms
MIP3 alpha; MIP3 alpha protein (Mouse); MIP 3 alpha; MIP-3 alpha; Exodus-1 protein; Macrophage Inflammatory Protein-3 alpha protein; MIP-3 alpha protein; MIP 3 alpha protein; CCL20 protein; LARC protein; MIP3 alpha active protein
Ordering
For Research Use Only!
Host
Mouse
Purity/Purification
> 98% pure
Form/Format
Supplied as a lyophilized powder.
Sequence
Region of MIP3 alpha protein corresponding to amino acids ASNYDCCLSY IQTPLPSRAI VGFTRQMADE ACDINAIIFH TKKRKSVCAD PKQNWVKRAV NLLSLRVKKM.
Sequence Length
96
Applicable Applications for MIP3 alpha active protein
User optimized
Protein Type
Recombinant
Biological Significance
MIP-3 alpha is a CC chemokine that is expressed in the liver, lymph nodes, appendix, PBL and lung and signals through the CCR6 receptor. MIP-3 alpha is chemotactic towards lymphocytes and dendritic cells. Additionally, it promotes the adhesion of memory CD4+ T cells and inhibits colony formation of bone marrow myeloid immature progenitors.
Bioactivity
Determined by its ability to chemoattract Mouse CCR6 transfected HEK/293 cells using a concentration range of 0.1-10.0 ng/ml
Endotoxin Levels
Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
Expression System
E Coli
Preparation and Storage
Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Related Product Information for MIP3 alpha active protein
Purified recombinant Mouse MIP3 alpha protein
Product Categories/Family for MIP3 alpha active protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
7.9 kDa
NCBI Official Full Name
macrophage inflammatory protein 3 alpha
NCBI Official Synonym Full Names
chemokine (C-C motif) ligand 20
NCBI Official Symbol
Ccl20
NCBI Official Synonym Symbols
CKb4; LARC; ST38; MIP3A; MIP-3A; Scya20; MIP-3[a]; exodus-1
NCBI Protein Information
C-C motif chemokine 20
UniProt Protein Name
C-C motif chemokine
UniProt Gene Name
Ccl20
UniProt Entry Name
Q642U4_MOUSE

Uniprot Description

CCL20: Chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. Inhibits proliferation of myeloid progenitors in colony formation assays. May be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. Possesses antibacterial activity E.coli ATCC 25922 and S.aureus ATCC 29213. Belongs to the intercrine beta (chemokine CC) family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Chemokine; Secreted, signal peptide; Motility/polarity/chemotaxis

Cellular Component: extracellular space; extracellular region

Molecular Function: protein binding; chemokine activity; cytokine activity

Biological Process: immune response; positive regulation of interleukin-1 alpha biosynthetic process; chemotaxis; inflammatory response; positive regulation of nitric-oxide synthase biosynthetic process

Research Articles on MIP3 alpha

Similar Products

Product Notes

The MIP3 alpha ccl20 (Catalog #AAA539403) is an Active Protein produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's MIP3 alpha can be used in a range of immunoassay formats including, but not limited to, User optimized. Researchers should empirically determine the suitability of the MIP3 alpha ccl20 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Region of MIP3 alpha protein correspond ing to amino acids ASNYDCCLSY IQTPLPSRAI VGFTRQMADE ACDINAIIFH TKKRKSVCAD PKQNWVKRAV NLLSLRVKKM. It is sometimes possible for the material contained within the vial of "MIP3 alpha, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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