Mouse Zika virus NS1 Monoclonal Antibody
Zika virus NS1 antibody
Applications
ELISA, Lateral Flow
Purity
> 90% purePurified by DEAE column chromatography
Synonyms
Zika virus NS1; Monoclonal Antibody; Zika virus NS1 antibody; Monoclonal Zika antibody; Zika virus antibody; Zika NS1 antibody; Zika virus NS1 antigen antibody; Zika antibody; Anti-Zika antibody; Zika virus Non-Structural 1 antibody; Zika Non Structural 1 antibody; ZIKV antibody; ZIKV antigen antibody; ZIKV NS1 antibody; Anti- Zika NS1 antibody; anti-Zika virus NS1 antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1 kappa
Clone Number
M86640
Purity/Purification
> 90% pure
Purified by DEAE column chromatography
Purified by DEAE column chromatography
Form/Format
liquid in 15mM potassium phosphate, 0.85% NaCl, pH 7.2 with 0.05% sodium azide
Concentration
1.0mg/ml (varies by lot)
Applicable Applications for anti-Zika virus NS1 antibody
ELISA (EIA), Lateral Flow
Immunogen
Zika virus NS1 antibody was raised in mouse using recombinant Zika NS1 protein as the immunogen.
Note
Potenially suitable for assay development for detection of Zika NS1 protein.
Assay Information
Zika virus NS1 protein, catalog no. MBS5304719, was used as the immunogen for this antibody and can be used as a positive control.
Biological Significance
Zika virus (ZIKV), a Flaviviridae family member transmitted to humans by mosquitoes of the genus Aedes, was first isolated in Africa in 1947. It has been found to commonly circulate in tropical regions in Africa and Asia. As a member of the Flaviviridae family, ZIKV has a single positive sense RNA genome, which is initially translated as a single polyprotein which is then cleaved post-translationally into three structural proteins (C, PrM or M, and E) and seven nonstructural (NS) proteins (NS1, NS2A, NS2B, NS3, NS4A, NS4B and NS5). NS1 is required for viral replication inside cells and is also secreted into the extracellular space as a hexameric lipoprotein particle, which is involved in immune evasion and pathogenesis by interacting with components from both the innate and adaptive immune systems.
Implications in Disease
Many people infected with Zika virus will have mild or no symptoms while others will have fever, rash, joint pain, or conjunctivitis. People rarely die from Zika virus. Pregnant woman can pass Zika virus to her fetus causing microcephaly and other severe fetal brain defects.
Preparation and Storage
Store at 4 degree C.
Related Product Information for anti-Zika virus NS1 antibody
Mouse monoclonal Zika virus NS1 antibody
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Product Notes
The Zika virus NS1 (Catalog #AAA5304710) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Zika virus NS1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Lateral Flow. Researchers should empirically determine the suitability of the Zika virus NS1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Zika virus NS1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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