Testing Data
(Immunocytochemistry stain of COS7 using UCHL1 antibody (1:300).)
Mouse anti-Human UCHL1 Monoclonal Antibody | anti-UCHL1 antibody
UCHL1 Antibody
Gene Names
UCHL1; NDGOA; PARK5; PGP95; SPG79; PGP9.5; Uch-L1; HEL-117; PGP 9.5; HEL-S-53
Reactivity
Human
Applications
Western Blot, Immunocytochemistry
Purity
Affinity purified
Synonyms
UCHL1; Monoclonal Antibody; UCHL1 Antibody; Neuron cytoplasmic protein 9.5; PGP 9.5; Ubiquitin thioesterase L1; anti-UCHL1 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2b
Specificity
This antibody detects endogenous levels of UCHL1 and does not cross-react with related proteins.
Purity/Purification
Affinity purified
Form/Format
Purified mouse monoclonal in PBS(pH 7.4)containing with 0.2% sodium azide, 50% glycerol, 0.1%BSA.
Sequence Length
223
Applicable Applications for anti-UCHL1 antibody
Western Blot (WB), Immunocytochemistry (ICC)
Immunogen
Purified recombinant human UCHL1. protein fragments expressed in E Coli.
Cellular Localization
Cytoplasm
Testing Data
(Immunocytochemistry stain of COS7 using UCHL1 antibody (1:300).)
Testing Data
(Immunocytochemistry stain of COS7 using UCHL1 antibody (1:300).)
Testing Data #2
(Western blot detection of UCHL1 in U251,Raji&IMP32 cell lysates and using UCHL1 antibody (1:1000 diluted). Predicted band size: 25KDa Observed band size:25KDa.)
Testing Data #2
(Western blot detection of UCHL1 in U251,Raji&IMP32 cell lysates and using UCHL1 antibody (1:1000 diluted). Predicted band size: 25KDa Observed band size:25KDa.)
Related Product Information for anti-UCHL1 antibody
UniPort Summary Function: Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity
Entrez Summary: The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease.
Entrez Summary: The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease.
Product Categories/Family for anti-UCHL1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
25kDa
NCBI Official Full Name
ubiquitin carboxyl-terminal hydrolase isozyme L1
NCBI Official Synonym Full Names
ubiquitin C-terminal hydrolase L1
NCBI Official Symbol
UCHL1
NCBI Official Synonym Symbols
NDGOA; PARK5; PGP95; SPG79; PGP9.5; Uch-L1; HEL-117; PGP 9.5; HEL-S-53
NCBI Protein Information
ubiquitin carboxyl-terminal hydrolase isozyme L1
UniProt Protein Name
Ubiquitin carboxyl-terminal hydrolase isozyme L1
Protein Family
UniProt Gene Name
UCHL1
UniProt Synonym Gene Names
UCH-L1; PGP9.5
NCBI Description
The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease.[provided by RefSeq, Sep 2009]
Uniprot Description
Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity.
Research Articles on UCHL1
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Product Notes
The UCHL1 uchl1 (Catalog #AAA857921) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The UCHL1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's UCHL1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC). Researchers should empirically determine the suitability of the UCHL1 uchl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "UCHL1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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