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Flow Cytometry (FC/FACS) (Flow Cytometric analysis of HEK293T cells transfected with either recombinant UBXN2B protein (red) or empty vector (blue) stained using UBXN2B antibody)

Mouse UBXN2B Monoclonal Antibody | anti-UBXN2B antibody

UBXN2B antibody

Gene Names
UBXN2B; p37
Applications
Flow Cytometry, Functional Assay, Western Blot
Purity
UBXN2B antibody was purified by affinity chromatography.
Synonyms
UBXN2B; Monoclonal Antibody; UBXN2B antibody; Monoclonal UBXN2B; Anti-UBXN2B; UBXNB 2; UBXNB-2; anti-UBXN2B antibody
Ordering
For Research Use Only!
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
1G3
Purity/Purification
UBXN2B antibody was purified by affinity chromatography.
Form/Format
Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration
500 ug-1 mg/ml (varies by lot)
Sequence Length
331
Applicable Applications for anti-UBXN2B antibody
Flow Cytometry (FC/FACS), Western Blot (WB)
Application Notes
FC: 1:100
WB: 1:2000
Biological Significance
UBXN2B is an adapter protein required for Golgi and endoplasmic reticulum biogenesis. Involved in Golgi and endoplasmicreticulum maintenance during interphase and in their reassembly at the end of mitosis. The complex formed with VCP has membrane fusion activity; membrane fusion activity requires USO1-GOLGA2 tethering and BET1L. VCPIP1 is also required, but not its deubiquitinating activity.
Cross-Reactivity
Human
Immunogen
UBXN2B antibody was raised in mouse using a full length recombinant protein of human UBXN2B (NP_001071087) produced in HEK293T cells, as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.

Flow Cytometry (FC/FACS)

(Flow Cytometric analysis of HEK293T cells transfected with either recombinant UBXN2B protein (red) or empty vector (blue) stained using UBXN2B antibody)

Flow Cytometry (FC/FACS) (Flow Cytometric analysis of HEK293T cells transfected with either recombinant UBXN2B protein (red) or empty vector (blue) stained using UBXN2B antibody)

Western Blot (WB)

(Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant UBXN2B protein (Right) or empty vector (Left) detected with UBXN2B antibody)

Western Blot (WB) (Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant UBXN2B protein (Right) or empty vector (Left) detected with UBXN2B antibody)
Related Product Information for anti-UBXN2B antibody
Mouse monoclonal UBXN2B antibody
Product Categories/Family for anti-UBXN2B antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
37,077 Da
NCBI Official Full Name
UBX domain-containing protein 2B
NCBI Official Synonym Full Names
UBX domain protein 2B
NCBI Official Symbol
UBXN2B
NCBI Official Synonym Symbols
p37
NCBI Protein Information
UBX domain-containing protein 2B
UniProt Protein Name
UBX domain-containing protein 2B
UniProt Gene Name
UBXN2B
UniProt Entry Name
UBX2B_HUMAN

Uniprot Description

UBXN2B: Adapter protein required for Golgi and endoplasmic reticulum biogenesis. Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis. The complex formed with VCP has membrane fusion activity; membrane fusion activity requires USO1-GOLGA2 tethering and BET1L. VCPIP1 is also required, but not its deubiquitinating activity. Belongs to the NSFL1C family.

Protein type: Adaptor/scaffold; Endoplasmic reticulum

Chromosomal Location of Human Ortholog: 8q12.1

Cellular Component: Golgi apparatus; endoplasmic reticulum; nucleus; cytosol

Molecular Function: ubiquitin binding; protein phosphatase type 1 regulator activity

Biological Process: proteasomal ubiquitin-dependent protein catabolic process; regulation of catalytic activity; nuclear envelope reassembly; Golgi organization and biogenesis; autophagic vacuole formation

Research Articles on UBXN2B

Similar Products

Product Notes

The UBXN2B ubxn2b (Catalog #AAA833906) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's UBXN2B can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Western Blot (WB). FC: 1:100 WB: 1:2000. Researchers should empirically determine the suitability of the UBXN2B ubxn2b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "UBXN2B, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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