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Western Blot (WB) (Fig-1: Western blot analysis of TSLPR. Anti- TSLPR antibody was used at 2 ug/ml on human heart lysate.)

Mouse anti-Human TSLPR Monoclonal Antibody | anti-TSLPR antibody

Monoclonal Antibody to hTSLPR (Clone: ABM3B96)

Gene Names
CRLF2; CRL2; TSLPR; CRLF2Y
Reactivity
Human
Applications
Western Blot
Purity
Purified
Protein G Chromatography
Synonyms
TSLPR; Monoclonal Antibody; Monoclonal Antibody to hTSLPR (Clone: ABM3B96); Cytokine receptor-like factor 2; Cytokine receptor-like 2; IL-XR; Thymic stromal lymphopoietin protein receptor; TSLP receptor; CRL2; ILXR; anti-TSLPR antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2b Kappa
Clone Number
ABM3B96
Purity/Purification
Purified
Protein G Chromatography
Form/Format
25 ug in 50 ul/100 ug in 200 ul PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Sequence Length
371
Applicable Applications for anti-TSLPR antibody
Western Blot (WB)
Application Notes
WB: 2-4 ug/ml
Immunogen Information
A partial length recombinant TSLPR protein (amino acids 102-310) was used as the immunogen for this antibody.
Antigen
TSLPR
Preparation and Storage
Store the antibody at 4 degree C, stable for 6 months.
For long-term storage, store at -20 degree C.
Avoid repeated freeze and thaw cycles.

Western Blot (WB)

(Fig-1: Western blot analysis of TSLPR. Anti- TSLPR antibody was used at 2 ug/ml on human heart lysate.)

Western Blot (WB) (Fig-1: Western blot analysis of TSLPR. Anti- TSLPR antibody was used at 2 ug/ml on human heart lysate.)
Product Categories/Family for anti-TSLPR antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
29,360 Da
NCBI Official Full Name
Cytokine receptor-like factor 2
NCBI Official Synonym Full Names
cytokine receptor-like factor 2
NCBI Official Symbol
CRLF2
NCBI Official Synonym Symbols
CRL2; TSLPR; CRLF2Y
NCBI Protein Information
cytokine receptor-like factor 2
UniProt Protein Name
Cytokine receptor-like factor 2
UniProt Gene Name
CRLF2
UniProt Synonym Gene Names
CRL2; ILXR; TSLPR; TSLP receptor

NCBI Description

This gene encodes a member of the type I cytokine receptor family. The encoded protein is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Rearrangement of this gene with immunoglobulin heavy chain gene (IGH) on chromosome 14, or with P2Y purinoceptor 8 gene (P2RY8) on the same X or Y chromosomes is associated with B-progenitor acute lymphoblastic leukemia (ALL) and Down syndrome ALL. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014]

Uniprot Description

CRLF2: Receptor for thymic stromal lymphopoietin (TSLP). Forms a functional complex with TSLP and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5. Also activates JAK2. Implicated in the development of the hematopoietic system. Belongs to the type I cytokine receptor family. Type 5 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: Xp22.33 and Yp11.2

Research Articles on TSLPR

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Product Notes

The TSLPR crlf2 (Catalog #AAA668404) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Monoclonal Antibody to hTSLPR (Clone: ABM3B96) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TSLPR can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 2-4 ug/ml. Researchers should empirically determine the suitability of the TSLPR crlf2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TSLPR, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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