Mouse TrpM7 Ion Channel and Ser/Thr Kinase Monoclonal Antibody
Anti-TrpM7 Ion Channel and Ser/Thr Kinase Monoclonal Antibody
Reactivity
Human, mouse, rat
Applications
Immunoblot, Immunocytochemistry, Immunohistochemistry, Western Blot
Synonyms
TrpM7 Ion Channel and Ser/Thr Kinase; Monoclonal Antibody; Anti-TrpM7 Ion Channel and Ser/Thr Kinase Monoclonal Antibody; anti-TrpM7 Ion Channel and Ser/Thr Kinase antibody
Host
Mouse
Reactivity
Human, mouse, rat
Clonality
Monoclonal
Isotype
lgG1
Clone Number
S74-25
Specificity
TrpM7 Ion Channel and Ser/Thr Kinase
This antibody recognizes human, mouse, and rat TrpM7. It does not cross-react with TrpM6.
This antibody recognizes human, mouse, and rat TrpM7. It does not cross-react with TrpM6.
Form/Format
100ug in PBS, pH 7.4; 50% glycerol, 0.09% sodium azide. Purified by Protein G affinity chromatography.
Sequence Positions
1817-1863
Applicable Applications for anti-TrpM7 Ion Channel and Ser/Thr Kinase antibody
Immunoblot; Immunohistochemistry; Immunocytochemistry
Application Notes
Immunoblotting: use at 1-10ug/ml. A band of ~220kDa is detected. Immunohistochemistry and Immunocytochemistry. use at 0.1-1ug/ml. ImmunoUuorescence: use at 1-10ug/ml. These are recommended concentrations. User should determine optimal concentrations for their application. Positive control: COS cell lysate transiently transfected with TrpM7.
Antigen
Fusion protein aa 1817-1863 (cytoplasmic C-terminus) of mouse TrpM7 (accession no. Q923J1)
Dilution Instructions
Dilute in PBS or medium which is identical to that used in the assay system.
Preparation and Storage
This antibody is stable for at least one (1) year at -20 degree C. Avoid repeated freezing and thawing.
Related Product Information for anti-TrpM7 Ion Channel and Ser/Thr Kinase antibody
Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient. TRPs, mammalian homologs of the Drosophila transient receptor potential (trp) proteins, are ion channels that are thought to mediate capacitative calcium entry into cells. TrpM7 functions as an ion channel and a serine/threonine kinase. As an ion channel, it conducts calcium and monovalent cations to depolarize cells and increase intracellular calcium. As a kinase, it can phosphorylate itself and other substrates. This kinase activity is necessary for channel function.
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Product Notes
The TrpM7 Ion Channel and Ser/Thr Kinase (Catalog #AAA190574) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1817-1863. The Anti-TrpM7 Ion Channel and Ser/Thr Kinase Monoclonal Antibody reacts with Human, mouse, rat and may cross-react with other species as described in the data sheet. AAA Biotech's TrpM7 Ion Channel and Ser/Thr Kinase can be used in a range of immunoassay formats including, but not limited to, Immunoblot; Immunohistochemistry; Immunocytochemistry. Immunoblotting: use at 1-10ug/ml. A band of ~220kDa is detected. Immunohistochemistry and Immunocytochemistry. use at 0.1-1ug/ml. ImmunoUuorescence: use at 1-10ug/ml. These are recommended concentrations. User should determine optimal concentrations for their application. Positive control: COS cell lysate transiently transfected with TrpM7. Researchers should empirically determine the suitability of the TrpM7 Ion Channel and Ser/Thr Kinase for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TrpM7 Ion Channel and Ser/Thr Kinase, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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