Mouse anti-Human TRIM45 Monoclonal Antibody | anti-TRIM45 antibody

Anti-TRIM45 Antibody (clone 3G3) IHC-plus

Cat. Num. AAA249403

• Gene Names: TRIM45; RNF99
• Reactivity: Human
• Applications: Immunohistochemistry, Immunofluorescence
• Purity: Protein A/G purified
• Synonyms: TRIM45; Monoclonal Antibody; Anti-TRIM45 Antibody (clone 3G3) IHC-plus; Mouse Monoclonal [clone 3G3] (IgG1) to Human TRIM45; Human TRIM45; RING finger protein 99; RNF99; Tripartite motif containing 45; Tripartite motif-containing 45; anti-TRIM45 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG1
• Clone Number: 3G3
• Specificity: Human TRIM45
• Purity/Purification: Protein A/G purified
• Form/Format: PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide
• Concentration: 1 mg/ml (varies by lot)
• Sequence Length: 580

• Applicable Applications for anti-TRIM45 antibody: Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF)
• Application Notes: IF (1:100); IHC-P (10 ug/ml)
• Immunogen: TRIM45 antibody was raised against human recombinant protein fragment corresponding to amino acids 288-580 of human TRIM45(NP_079464) produced in E Coli.
• Immunogen Description: Human recombinant protein fragment corresponding to amino acids 288-580 of human TRIM45(NP_079464) produced in E Coli.
• Immunogen Type: Recombinant protein
• Target Species: Human
• Preparation and Storage: Store at -20 degree C. Minimize freezing and thawing.

Immunohistochemistry (IHC)

(Anti-TRIM45 antibody IHC staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

Immunofluorescence (IF)

(Anti-TRIM45 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY TRIM45.)

Related Product Information for anti-TRIM45 antibody

TRIM45 Antibody, RING finger protein 99 Antibody, RNF99 Antibody, Tripartite motif containing 45 Antibody, Tripartite motif-containing 45 Antibody Description: May act as a transcriptional repressor in mitogen-activated protein kinase signaling pathway.

NCBI and Uniprot Product Information

• NCBI GI #: 224548921
• NCBI GeneID: 80263
• NCBI Accession #: NP_079464.2
• NCBI GenBank Nucleotide #: NM_025188.3
• UniProt Accession #: Q9H8W5; Q53GN0; Q5T2K4; Q5T2K5; Q8IYV6
• Molecular Weight: 62,475 Da
• NCBI Official Full Name: tripartite motif-containing protein 45 isoform 1
• NCBI Official Synonym Full Names: tripartite motif containing 45
• NCBI Official Symbol: TRIM45
• NCBI Official Synonym Symbols: RNF99
• NCBI Protein Information: tripartite motif-containing protein 45
• UniProt Protein Name: Tripartite motif-containing protein 45
• Protein Family: Tripartite motif-containing protein
• UniProt Gene Name: TRIM45
• UniProt Synonym Gene Names: RNF99
• UniProt Entry Name: TRI45_HUMAN

NCBI Description

This gene encodes a member of the tripartite motif family. The encoded protein may function as a transcriptional repressor of the mitogen-activated protein kinase pathway. Alternatively spliced transcript variants have been described.[provided by RefSeq, Mar 2009]

Uniprot Description

TRIM45: May act as a transcriptional repressor in mitogen- activated protein kinase signaling pathway. Belongs to the TRIM/RBCC family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: 1p13.1

Cellular Component: cytoplasm; intercellular bridge; nucleoplasm

Molecular Function: zinc ion binding