Human inhibin, beta B ELISA Kit | INHBB elisa kit

human inhibin beta-B, Inhbb ELISA Kit

Cat. Num. AAA702217

• Reactivity: Human
• Synonyms: inhibin; beta B; human inhibin beta-B; Inhbb ELISA Kit; MGC157939; Inhibin; beta-2; activin AB beta polypeptide; inhibin beta B subunit; INHBB elisa kit

• Reactivity: Human
• Specificity: This assay has high sensitivity and excellent specificity for detection of Human INHBB. No significant cross-reactivity or interference between Human INHBB and analogues was observed.
• Sequence Length: 407

• Detection Range: 1.6 pg/ml-400 pg/ml
• Sensitivity: 1 pg/ml
• Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%; Three samples of known concentration were tested twenty times on one plate to assess.; Inter-assay Precision (Precision between assays): CV% is less than 10%; Three samples of known concentration were tested in twenty assays to assess.
• Detection Wavelength: 450 nm
• Sample Volume: 50-100ul
• Preparation and Storage: Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for INHBB elisa kit

Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an goat-anti-rabbit antibody. Standards or samples are then added to the appropriate microtiter plate wells with a HRP-conjugated Inhbb and antibody preparation specific for Inhbb and incubated. Then substrate solutions are added to each well. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of Inhbb in the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 154813204
• NCBI GeneID: 3625
• NCBI Accession #: NP_002184.2
• NCBI GenBank Nucleotide #: NM_002193.2
• UniProt Accession #: P09529; Q53T31; Q8N1D3
• Molecular Weight: 45,122 Da
• NCBI Official Full Name: inhibin beta B chain preproprotein
• NCBI Official Synonym Full Names: inhibin, beta B
• NCBI Official Symbol: INHBB
• NCBI Protein Information: inhibin beta B chain; Inhibin, beta-2; activin beta-B chain; activin AB beta polypeptide
• UniProt Protein Name: Inhibin beta B chain
• Protein Family: Inhibin
• UniProt Gene Name: INHBB
• UniProt Entry Name: INHBB_HUMAN

NCBI Description

The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. [provided by RefSeq, Jul 2008]

Uniprot Description

Function: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.