Mouse TLR3 Monoclonal Antibody
TLR3 (Toll Like Receptor 3, Toll-like Receptor 3, TLR 3, TLR-3, CD283, CD283 Antigen) (FITC)
Reactivity
Canine, Human
Applications
Flow Cytometry, Functional Assay
Purity
Affinity PurifiedPurified.
Synonyms
TLR3; Monoclonal Antibody; TLR3 (Toll Like Receptor 3; Toll-like Receptor 3; TLR 3; TLR-3; CD283; CD283 Antigen) (FITC); Anti -TLR3 (Toll Like Receptor 3; anti-TLR3 antibody
Host
Mouse
Reactivity
Canine, Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
9G280
Specificity
Recognizes human Toll-like receptor 3 (TLR3, CD283). Species crossreactivity: dog.
Purity/Purification
Affinity Purified
Purified.
Purified.
Form/Format
Supplied as a liquid in PBS, 1% BSA, 0.02% sodium azide. Labeled with fluorescein isothiocyanate (FITC).
Applicable Applications for anti-TLR3 antibody
Flow Cytometry (FC/FACS)
Application Notes
Can be used for intracellular Flow Cytometry.
Dilution: Flow Cytometry: 1:10
Dilution: Flow Cytometry: 1:10
Immunogen
Human TLR3.
Preparation and Storage
For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. FITC conjugates are sensitive to light.
Related Product Information for anti-TLR3 antibody
Toll-like receptors (TLR) are highly conserved throughout evolution and have been implicated in the innate defense to many pathogens. In Drosophila toll is required for the anti-fungal response, while the related 18-wheeler is involved in antibacterial defenses. In mammals, TLR identified as type I transmembrane signalling receptors with pattern recognition capabilities, have been implicated in the innate host defense to pathogens. As investigated so far all functional characterized TLR signal via the TLR/IL-1 receptor (IL-1R) pathway where recruitment of MyD88 seems to be essential. Viral replication within infected cells results in generation of dsRNA which can stimulate immune cells. Recent data show that TLR3 (CD283) acts as a receptor involved in the recognition of dsRNA, indicating a role for TLR3 in viral recognition and innate defense.
Product Categories/Family for anti-TLR3 antibody
NCBI and Uniprot Product Information
Similar Products
Product Notes
The TLR3 (Catalog #AAA607755) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The TLR3 (Toll Like Receptor 3, Toll-like Receptor 3, TLR 3, TLR-3, CD283, CD283 Antigen) (FITC) reacts with Canine, Human and may cross-react with other species as described in the data sheet. AAA Biotech's TLR3 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS). Can be used for intracellular Flow Cytometry. Dilution: Flow Cytometry: 1:10. Researchers should empirically determine the suitability of the TLR3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TLR3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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