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Testing Data (TIM-2 transfected NRK cells stained with Rat anti Mouse TIM-2.)

Rat anti-Mouse TIM-2 Monoclonal Antibody | anti-TIM-2 antibody

TIM-2 (T-cell Immunoglobulin Mucin 2, Timd2, Tim2) (MaxLight 750)

Gene Names
Timd2; G9D3; Tim2; TIM-2; C78111; AA816106; AU019358; AU019662
Reactivity
Mouse
Applications
Flow Cytometry, Functional Assay, Immunoprecipitation, Western Blot
Purity
Purified by protein G affinity chromatography from tissue culture supernatant.
Synonyms
TIM-2; Monoclonal Antibody; TIM-2 (T-cell Immunoglobulin Mucin 2; Timd2; Tim2) (MaxLight 750); anti-TIM-2 antibody
Ordering
For Research Use Only!
Host
Rat
Reactivity
Mouse
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
RMT2-25
Specificity
Recognizes mouse Tim-2.
Purity/Purification
Purified by protein G affinity chromatography from tissue culture supernatant.
Form/Format
Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight750.
Applicable Applications for anti-TIM-2 antibody
Flow Cytometry (FC/FACS), Immunoprecipitation (IP), Western Blot (WB)
Immunogen
Tim-2-Ig, consisting of aa1-230 from mouse Tim-2, coupled with the Fc portion of mouse IgG2a.
Conjugate
MaxLight750
Preparation and Storage
Store at 4 degree C. Do Not Freeze.

Testing Data

(TIM-2 transfected NRK cells stained with Rat anti Mouse TIM-2.)

Testing Data (TIM-2 transfected NRK cells stained with Rat anti Mouse TIM-2.)
Product Categories/Family for anti-TIM-2 antibody
References
1. Kawamoto, T. et al. (2011) Anti-T cell immunoglobulin and mucin domain-2 monoclonal antibody exacerbates collagen-induced arthritis by stimulating B cells. Arthritis Res. Ther. 13: R47Further Reading. 2. Freeman, G.J. et al. (2010) TIM genes: a family of cell surface phosphatidylserine receptors that regulate innate and adaptive immunity.Immunol. Rev. 235: 172-189.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
33,504 Da
NCBI Official Full Name
T-cell immunoglobulin and mucin domain-containing protein 2
NCBI Official Synonym Full Names
T cell immunoglobulin and mucin domain containing 2
NCBI Official Symbol
Timd2
NCBI Official Synonym Symbols
G9D3; Tim2; TIM-2; C78111; AA816106; AU019358; AU019662
NCBI Protein Information
T-cell immunoglobulin and mucin domain-containing protein 2; T-cell immunoglobulin and mucin domain containing 2; T-cell immunoglobulin mucin receptor 2; T-cell membrane protein 2; TIMD-2
UniProt Protein Name
T-cell immunoglobulin and mucin domain-containing protein 2
UniProt Gene Name
Timd2
UniProt Synonym Gene Names
Tim2; TIMD-2; TIM-2
UniProt Entry Name
TIMD2_MOUSE

Uniprot Description

TIM-2: Probable receptor for SEMA4A involved in the regulation of T-cell function. The interaction with SEMA4A enhances T-cell activation. Belongs to the immunoglobulin superfamily. TIM family.

Protein type: Membrane protein, integral

Cellular Component: membrane; integral to membrane; plasma membrane

Research Articles on TIM-2

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Product Notes

The TIM-2 timd2 (Catalog #AAA6257425) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The TIM-2 (T-cell Immunoglobulin Mucin 2, Timd2, Tim2) (MaxLight 750) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TIM-2 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Immunoprecipitation (IP), Western Blot (WB). Researchers should empirically determine the suitability of the TIM-2 timd2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TIM-2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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