Mouse anti-Human, Mouse Thr181 phosphorylated Tau Monoclonal Antibody
mAb anti-human Thr181 phosphorylated Tau
Reactivity
Human, Mouse
Applications
Western Blot
Purity
Protein G affinity purified
Synonyms
Thr181 phosphorylated Tau; Monoclonal Antibody; mAb anti-human Thr181 phosphorylated Tau; Tau Protein (Thr181 Phosphorylated); Mouse monoclonal antibody against Thr181 phosphorylated Tau protein; anti-Thr181 phosphorylated Tau antibody
Host
Mouse
Reactivity
Human, Mouse
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
7G9
Specificity
This antibody recognizes the above mentioned peptide and its KLH conjugate, but not recognizes KLH alone. The antibody detected a 46kD band in mouse brain tissue lysate.
Tau Protein (Thr181 Phosphorylated)
Tau Protein (Thr181 Phosphorylated)
Purity/Purification
Protein G affinity purified
Form/Format
Lyophilized from a solution in 0.01M PBS pH7.2
Applicable Applications for anti-Thr181 phosphorylated Tau antibody
Western Blot (WB)
Target Protein
Human Thr181 phosphorylated Tau
Immunogen
KLH conjugated with a short peptide [Ala-Pro-Lys-Thr(p)-Pro-Pro-Ser-Ser-Gly-Glu-Cys], corresponding to the amino acid sequence 177-187 on the phosphorylated Tau protein.
Myeloma
Sp2/0-Ag14
Light Chain
Kappa
Reconstitution
Double distilled water is recommended to adjust the final concentration to 1.00mg/mL. Avoid repeated freeze and thaw cycle.
Research Area
Alzheimer's disease and other neurodegenerative diseases
Preparation and Storage
Store at -20 degree C
Related Product Information for anti-Thr181 phosphorylated Tau antibody
Description: Mouse monoclonal antibody against Thr181 phosphorylated Tau protein
background: Tau is a highly soluble microtubule associated protein found in high concentration in neuron of central nervous system. The main function of the protein is stabilizing the microtubule in nerve fibre (axon). There are six tau isoforms which are formed by alternate splicing. Hyperphosphorylation of Tau protein results in aggregation and formation of neurofibrillary tangles, which is significantly associated with cognitive impairment in Alzheimer's disease. Tau Thr181 phosphorylation has been used as a biomarker for the differentiation of Alzheimer's disease and other primary dementia such as dementia with Lewy bodies.
background: Tau is a highly soluble microtubule associated protein found in high concentration in neuron of central nervous system. The main function of the protein is stabilizing the microtubule in nerve fibre (axon). There are six tau isoforms which are formed by alternate splicing. Hyperphosphorylation of Tau protein results in aggregation and formation of neurofibrillary tangles, which is significantly associated with cognitive impairment in Alzheimer's disease. Tau Thr181 phosphorylation has been used as a biomarker for the differentiation of Alzheimer's disease and other primary dementia such as dementia with Lewy bodies.
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Product Notes
The Thr181 phosphorylated Tau (Catalog #AAA592364) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The mAb anti-human Thr181 phosphorylated Tau reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Thr181 phosphorylated Tau can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the Thr181 phosphorylated Tau for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Thr181 phosphorylated Tau, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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