Mouse anti-Human THOP1 Monoclonal Antibody | anti-THOP1 antibody
THOP1 (Thimet Oligopeptidase, TOP, Endopeptidase 24.15, EP24.15, MP78)
Gene Names
THOP1; TOP; MP78; EP24.15; MEPD_HUMAN
Reactivity
Human
Applications
ELISA, Western Blot
Purity
AscitesAscites
Synonyms
THOP1; Monoclonal Antibody; THOP1 (Thimet Oligopeptidase; TOP; Endopeptidase 24.15; EP24.15; MP78); Anti -THOP1 (Thimet Oligopeptidase; anti-THOP1 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgM,k
Clone Number
2B4
Specificity
Recognizes human THOP1.
Purity/Purification
Ascites
Ascites
Ascites
Form/Format
Supplied as a liquid in ascites fluid.
Sequence
ILKELVTLRAQKSRLLGFHTHADYVLEMNMAKTSQTVATFLDELAQKLKPLGEQERAVILELKRAECERRGLPFDGRIRAWDMRYYMNQVEETRYCVDQN
Applicable Applications for anti-THOP1 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in ELISA and Western Blot.
Immunogen
Partial recombinant corresponding to aa255-355 from human THOP1 with GST tag.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Product Categories/Family for anti-THOP1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
78,840 Da
NCBI Official Full Name
thimet oligopeptidase
NCBI Official Synonym Full Names
thimet oligopeptidase 1
NCBI Official Symbol
THOP1
NCBI Official Synonym Symbols
TOP; MP78; EP24.15; MEPD_HUMAN
NCBI Protein Information
thimet oligopeptidase; endopeptidase 24.15
UniProt Protein Name
Thimet oligopeptidase
Protein Family
UniProt Gene Name
THOP1
UniProt Entry Name
THOP1_HUMAN
Uniprot Description
Function: Involved in the metabolism of neuropeptides under 20 amino acid residues long. Involved in cytoplasmic peptide degradation. Able to degrade the beta-amyloid precursor protein and generate amyloidogenic fragments.
Catalytic activity: Preferential cleavage of bonds with hydrophobic residues at P1, P2 and P3' and a small residue at P1' in substrates of 5 to 15 residues.
Cofactor: Binds 1 zinc ion per subunit.
Subunit structure: Monomer
By similarity.
Subcellular location: Cytoplasm.
Sequence similarities: Belongs to the peptidase M3 family.
Research Articles on THOP1
Similar Products
Product Notes
The THOP1 thop1 (Catalog #AAA649205) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The THOP1 (Thimet Oligopeptidase, TOP, Endopeptidase 24.15, EP24.15, MP78) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's THOP1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in ELISA and Western Blot. Researchers should empirically determine the suitability of the THOP1 thop1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: ILKELVTLRA QKSRLLGFHT HADYVLEMNM AKTSQTVATF LDELAQKLKP LGEQERAVIL ELKRAECERR GLPFDGRIRA WDMRYYMNQV EETRYCVDQN. It is sometimes possible for the material contained within the vial of "THOP1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
