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Western Blot (WB) (THOC1 Antibody (N-term) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the THOC1 antibody detected the THOC1 protein (arrow).)

Mouse anti-Human THOC1 Monoclonal Antibody | anti-THOC1 antibody

THOC1, NT (THOC1, HPR1, THO complex subunit 1, Nuclear matrix protein p84, hTREX84) (FITC)

Gene Names
THOC1; P84; HPR1; P84N5
Reactivity
Human
Applications
Western Blot
Purity
Purified by Protein G Affinity Chromatography
Synonyms
THOC1; Monoclonal Antibody; NT (THOC1; HPR1; THO complex subunit 1; Nuclear matrix protein p84; hTREX84) (FITC); hTREX84; anti-THOC1 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG3,k
Clone Number
301CT40.5.1
Purity/Purification
Purified by Protein G Affinity Chromatography
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein isothiocyanate (FITC).
Applicable Applications for anti-THOC1 antibody
FLISA, Western Blot (WB)
Application Notes
FLISA: 1:1000
WB: 1:100-250
Applications are based on unconjugated antibody.
Immunogen
THOC1 Mab is generated from mouse immunized with THOC1 recombinant protein.
Conjugate
FITC
Special Handling
Light sensitive
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Western Blot (WB)

(THOC1 Antibody (N-term) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the THOC1 antibody detected the THOC1 protein (arrow).)

Western Blot (WB) (THOC1 Antibody (N-term) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the THOC1 antibody detected the THOC1 protein (arrow).)
Related Product Information for anti-THOC1 antibody
HPR1 is part of the TREX (transcription/export) complex, which includes TEX1 (MIM 606929), THO2 (MIM 300395), ALY (MIM 604171), and UAP56 (MIM 142560).
Product Categories/Family for anti-THOC1 antibody
References
Davila, S., et al. Genes Immun. 11(3):232-238(2010) Liu, Y., et al. Mol. Psychiatry (2010) In press Boyne, J.R., et al. PLoS Pathog. 4 (10), E1000194 (2008) Ferreira, M.A., et al. Nat. Genet. 40(9):1056-1058(2008) Yang, J., et al. Ann. Clin. Lab. Sci. 38(2):105-112(2008)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
43,359 Da
NCBI Official Full Name
Homo sapiens THO complex 1 (THOC1), mRNA
NCBI Official Synonym Full Names
THO complex 1
NCBI Official Symbol
THOC1
NCBI Official Synonym Symbols
P84; HPR1; P84N5
NCBI Protein Information
THO complex subunit 1; hTREX84; nuclear matrix protein p84; tho1
UniProt Protein Name
THO complex subunit 1
UniProt Gene Name
THOC1
UniProt Synonym Gene Names
HPR1; Tho1; p84N5
UniProt Entry Name
THOC1_HUMAN

NCBI Description

HPR1 is part of the TREX (transcription/export) complex, which includes TEX1 (MIM 606929), THO2 (MIM 300395), ALY (MIM 604171), and UAP56 (MIM 142560).[supplied by OMIM, Nov 2010]

Uniprot Description

Tho1: a protein associated the nuclear matrix. Part of the TREX (transcription/export) complex. The TREX complex is recruited to transcribed genes and travels with the RNA polymerase during elongation. It may physically link proteins that function in transcription and in RNA export.

Protein type: Spliceosome

Chromosomal Location of Human Ortholog: 18p11.32

Cellular Component: nucleoplasm; intercellular bridge; nuclear matrix; cytoplasm; nuclear speck; nucleus

Molecular Function: protein binding; DNA binding; RNA binding

Biological Process: RNA processing; mRNA export from nucleus; transcription, DNA-dependent; negative regulation of isotype switching to IgA isotypes; apoptosis; RNA splicing; positive regulation of RNA elongation; regulation of DNA recombination; intronless viral mRNA export from host nucleus; signal transduction; mRNA processing; regulation of RNA elongation; replication fork processing

Research Articles on THOC1

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Product Notes

The THOC1 thoc1 (Catalog #AAA6121421) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The THOC1, NT (THOC1, HPR1, THO complex subunit 1, Nuclear matrix protein p84, hTREX84) (FITC) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's THOC1 can be used in a range of immunoassay formats including, but not limited to, FLISA, Western Blot (WB). FLISA: 1:1000 WB: 1:100-250 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the THOC1 thoc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "THOC1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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