Western Blot (WB)
()
Mouse TCPTP Monoclonal Antibody | anti-TCPTP antibody
TCPTP antibody
Applications
ELISA, Western Blot
Purity
TCPTP antibody was purified by ammonium sulfate precipitation
Synonyms
TCPTP; Monoclonal Antibody; TCPTP antibody; Monoclonal TCPTP; Anti-TCPTP; PTPN2; protein tyrosine phosphatase; non-receptor type 2; BOS_22287; MPTP; phosphoprotein phosphatase; protein-tyrosine phosphatase PTP-2; protein-tyrosine phosphatase PTP-S; ptn2; Ptpt; T cell protein-tyrosine phosphatase; T-cell protein tyrosine phosphatase; TCELLPTP; TC-PTP; tyrosine-protein phosphatase non-receptor type 2; anti-TCPTP antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG2b kappa
Clone Number
T25-AF3B7
Purity/Purification
TCPTP antibody was purified by ammonium sulfate precipitation
Form/Format
Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol
Applicable Applications for anti-TCPTP antibody
ELISA (EIA), Western Blot (WB)
Application Notes
WB: 1:2000
Biological Significance
T cell protein tyrosine phosphatase (TCPTP), also known as PTPT and PTPN2, is an enzyme that removes phosphate groups covalently attached to tyrosine residues in proteins. TCPTP is ubiquitously expressed with particularly high expression in hematopoietic tissues and exists as two forms: an endoplasmic reticulum-targeted 48- kDa form (TC48) and a nuclear 45- kDa form (TC45). Although targeted to the nucleus, TC45 can exit in response to specific stimuli to dephosphorylate cytoplasmic substrates. TC-PTP is a negative regulator of the Jak/Stat cytokine signaling pathway. TCPTP is the PTP most closely related to PTP1B, with 72% sequence identity and 86% similarity in the catalytic domain.
Cross-Reactivity
Human
Immunogen
TCPTP antibody was raised in Mouse using a recombinant human protein purified from E Coli as the immunogen
Preparation and Storage
Aliquot and store for 1 year at -20 degree C, avoid freeze/thaw cycles
Western Blot (WB)
()
Western Blot (WB)
()
Related Product Information for anti-TCPTP antibody
Mouse monoclonal TCPTP antibody
Product Categories/Family for anti-TCPTP antibody
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Product Notes
The TCPTP (Catalog #AAA833344) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's TCPTP can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). WB: 1:2000. Researchers should empirically determine the suitability of the TCPTP for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TCPTP, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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