Mouse anti-Human TCF7L2 Monoclonal Antibody | anti-TCF7L2 antibody

TCF7L2 (Transcription Factor 7-like 2, HMG Box Transcription Factor 4, T-cell-specific Transcription Factor 4, T-cell Factor 4, TCF-4, hTCF-4, TCF4) (AP)

Cat. Num. AAA6134148

• Gene Names: TCF7L2; TCF4; TCF-4
• Reactivity: Human
• Applications: ELISA, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: TCF7L2; Monoclonal Antibody; TCF7L2 (Transcription Factor 7-like 2; HMG Box Transcription Factor 4; T-cell-specific Transcription Factor 4; T-cell Factor 4; TCF-4; hTCF-4; TCF4) (AP); anti-TCF7L2 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG1,k
• Clone Number: 1B1
• Specificity: Recognizes human TCF7L2.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).
• Sequence Length: 2165

• Applicable Applications for anti-TCF7L2 antibody: ELISA (EIA), Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: Full length recombinant corresponding to aa1-456 from human TCF7L2 (AAH32656) with GST tag. MW of the GST tag alone is 26kD.
• Immunogen Sequence: MPQLNGGGGDDLGANDELISFKDEGEQEEKSSENSSAERDLADVKSSLVNESETNQNSSSDSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGSLSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGWQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPPNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETNEHSECFLNPCLSLPPITGEKKSAFATYKVKAAASAHPLQMEAY
• Conjugate: AP
• Preparation and Storage: Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(TCF7L2 monoclonal antibody, Western Blot analysis of TCF7L2 expression in HeLa NE.)

Western Blot (WB)

(Western Blot analysis of TCF7L2 expression in transfected 293T cell line by TCF7L2 monoclonal antibody. Lane 1: TCF7L2 transfected lysate (50.6kD). Lane 2: Non-transfected lysate.)

Western Blot (WB)

(Western blot analysis of TCF7L2 over-expressed 293 cell line, cotransfected with TCF7L2 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with TCF7L2 monoclonal antibody GAPDH (36.1kD) used as specificity and loading control.)

Related Product Information for anti-TCF7L2 antibody

This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes. Several transcript variants encoding multiple different isoforms have been found for this gene.

Product Categories/Family for anti-TCF7L2 antibody

Antibodies; Transcription Factors

NCBI and Uniprot Product Information

• NCBI GI #: 21619668
• NCBI GeneID: 6934
• NCBI Official Full Name: Homo sapiens transcription factor 7-like 2 (T-cell specific, HMG-box), mRNA
• NCBI Official Synonym Full Names: transcription factor 7 like 2
• NCBI Official Symbol: TCF7L2
• NCBI Official Synonym Symbols: TCF4; TCF-4
• NCBI Protein Information: transcription factor 7-like 2
• Protein Family: Transcription factor

NCBI Description

This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes. Several transcript variants encoding multiple different isoforms have been found for this gene.[provided by RefSeq, Oct 2010]