Mouse Syk Monoclonal Antibody | anti-Syk antibody
Syk, p72 (PE)
Reactivity
Human, Mouse, Rat
Applications
Immunoprecipitation, Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
Syk; Monoclonal Antibody; p72 (PE); anti-Syk antibody
Host
Mouse
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Isotype
IgG1
Clone Number
6A464
Specificity
Recognizes protein tyrosine kinase p72syk (Syk), a 72kD non-receptor tyrosine kinase, critical for immunoreceptor signaling in haematopoietic cells, but also expressed by nonhaematopoietic cells, including fibroblasts, endothelial cells, and hepatocytes. Species Cross Reactivity: Human, mouse and rat.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. Labeled with R-Phycoerythrin (PE).
Applicable Applications for anti-Syk antibody
Immunoprecipitation (IP), Western Blot (WB)
Immunogen
Recombinant fragment corresponding to amino acids 5-360 of human Syk.
Conjugate
PE
Preparation and Storage
Store at 4 degree C. Do Not Freeze.
Product Categories/Family for anti-Syk antibody
References
1. Amoui, M. et al. (1997). Direct interaction of Syk and Lyn protein tyrosine kinases in rat basophilic leukemia cells activated via type I Fc epsilon receptors. Eur. J. Immunol. 27(1): 321-328. 2. Tolar, P. et al. (1997). Protein tyrosine kinase Syk is involved in Thy-1 signaling in rat basophilic leukemia cells. Eur. J. Immunol. 27(12): 3389-3397. 3. Manetz, T.S. et al. (2001). Vav1 regulates phospholipase C gamma activation and calcium responses in mast cells. Mol. Cell. Biol. 21(11): 3763-3774. 4. Swann, P.G.et al. (1999). Requirement for a negative charge at Threonine 60 of the FcR gamma for complete activation of Syk. J. Biol. Chem. 274(33): 23068-23077. 5. Arudchandran, R.et al. (2000). The src homology 2 domain of Vav is required for its compartmentation to the plasma membrane and activation of c-Jun NH2-terminal kinase 1. J. Exp. Med. 191(1): 47-59.
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Product Notes
The Syk (Catalog #AAA6252192) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Syk, p72 (PE) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Syk can be used in a range of immunoassay formats including, but not limited to, Immunoprecipitation (IP), Western Blot (WB). Researchers should empirically determine the suitability of the Syk for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Syk, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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