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Rat, Mouse Substance P/HRP Bispecific Chimeric Monoclonal Antibody

Substance P/HRP Bispecific Chimeric Monoclonal Antibody (P4C1)

Reactivity
Human
Predicted: All Mammals, Crab, Pigeons
Applications
Immunohistochemistry, ELISA
Synonyms
Substance P/HRP Bispecific Chimeric; Monoclonal Antibody; Substance P/HRP Bispecific Chimeric Monoclonal Antibody (P4C1); Substance P; tachykinin; neuropeptide; neurokinin; Sp; anti-tachykinin; anti-neuropeptide; anti-neurokinin; anti-SP; anti-Substance P/HRP Bispecific Chimeric antibody
Ordering
For Research Use Only!
Host
Rat, Mouse
Reactivity
Human
Predicted: All Mammals, Crab, Pigeons
Clonality
Monoclonal
Isotype
IgG2a/IgG1
Clone Number
P4C1
Specificity
This is a bispeciflc antibody which recognizes (A) Substance P and (B) Horseradish peroxidase types I, II, VI, IX, X. This antibody recognizes the COOH-terminal end of substance P. It does not recognize Leu-or Met enkephalin, somatostatin or beta-endorphin; cross-reactivity with eledoisin: 5%. It recognizes Substance P in post-mortem tissue of the human brain.
Form/Format
Lyophilized tissue culture supernatant
Sequence Length
49
Applicable Applications for anti-Substance P/HRP Bispecific Chimeric antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
If reconstituted in 2 ml: IHC: 1:100-1:200
Immunogen
Substance P and Full Lenght HRP
Preservative
0.05% thimerosal
Preparation and Storage
Lyophilized antibody can be kept at 4 degree C for up to 3 months and should be kept at-20 degree C for long-term storage.
To avoid freeze-thaw cycles, reconstituted antibody should be aliquoted before freezing for short-term storage (-20 degree C) or for long-term storage (-SO degree C). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-Substance P/HRP Bispecific Chimeric antibody
This antibody is a bispeciflc monoclonal antibody capable of simultaneously recognize the horseradish peroxidase (HRP) and Substance P. Bi-speciflc monoclonal antibodies have been successfully used in one step immunocytochemistry and immuno-dot assays. These results demonstrated that bispeciflc antibodies can be applied in quick and simple staining procedures and provide intense immunostaining. The P4Cl antibody has been successfully used in immunoassays and immunohistochemistry. Light and electron micrographs of rat tissue developed using this antibody clearly demonstrate substance P immunoreactive sites with very minimal non-specific background binding.
References
1. Ribeiro-

NCBI and Uniprot Product Information

NCBI GI #
Molecular Weight
5,522 Da
NCBI Official Full Name
substance P, partial
UniProt Protein Name
Substance P

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Product Notes

The Substance P/HRP Bispecific Chimeric (Catalog #AAA588002) is an Antibody produced from Rat, Mouse and is intended for research purposes only. The product is available for immediate purchase. The Substance P/HRP Bispecific Chimeric Monoclonal Antibody (P4C1) reacts with Human Predicted: All Mammals, Crab, Pigeons and may cross-react with other species as described in the data sheet. AAA Biotech's Substance P/HRP Bispecific Chimeric can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA). If reconstituted in 2 ml: IHC: 1:100-1:200. Researchers should empirically determine the suitability of the Substance P/HRP Bispecific Chimeric for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Substance P/HRP Bispecific Chimeric, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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