Quality Control
(Western blot analysis of immunized recombinant protein, using anti-SOX12 monoclonal antibody. )
Mouse anti-Human SOX12 Monoclonal Antibody | anti-SOX12 antibody
Mouse monoclonal antibody Anti-Human SOX12
Quality Control
(Western blot analysis of immunized recombinant protein, using anti-SOX12 monoclonal antibody. )
Quality Control
(Western blot analysis of immunized recombinant protein, using anti-SOX12 monoclonal antibody. )
Quality Control #2
(Arrow indicates the region of immunized recombinant protein carrying 50-200 amino acids.)
Quality Control #2
(Arrow indicates the region of immunized recombinant protein carrying 50-200 amino acids.)
Western Blot (WB)
(Detection of human SOX12 by Western blot.Samples: Whole cell lysate (25 ug) from HT-1080 cells. [Lot No. 86C2a-1]Predicted molecular weight: 34 kDa)
Western Blot (WB)
(Detection of human SOX12 by Western blot.Samples: Whole cell lysate (25 ug) from HT-1080 cells. [Lot No. 86C2a-1]Predicted molecular weight: 34 kDa)
Immunocytochemistry (ICC)
(Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X-100 in PBS. The cells were immunostained with anti-SOX12 mAb. [Lot No. 86C2a-1])
Immunocytochemistry (ICC)
(Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X-100 in PBS. The cells were immunostained with anti-SOX12 mAb. [Lot No. 86C2a-1])
NCBI and Uniprot Product Information
NCBI Description
Members of the SOX family of transcription factors are characterized by the presence of a DNA-binding high mobility group (HMG) domain, homologous to the HMG box of sex-determining region Y (SRY). Forming a subgroup of the HMG domain superfamily, SOX proteins have been implicated in cell fate decisions in a diverse range of developmental processes. SOX transcription factors have diverse tissue-specific expression patterns during early development and have been proposed to act as target-specific transcription factors and/or as chromatin structure regulatory elements. The protein encoded by this gene was identified as a SOX family member based on conserved domains, and its expression in various tissues suggests a role in both differentiation and maintenance of several cell types. [provided by RefSeq, Jan 2013]
Uniprot Description
SOX12: Binds to the sequence 5'-AACAAT-3'.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 20p13
Cellular Component: nucleus
Molecular Function: DNA binding
Biological Process: regulation of transcription from RNA polymerase II promoter; cell fate commitment; transcription, DNA-dependent; spinal cord development; positive regulation of transcription from RNA polymerase II promoter; protein-DNA complex assembly
Research Articles on SOX12
Similar Products
Product Notes
The SOX12 sox12 (Catalog #AAA120310) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse monoclonal antibody Anti-Human SOX12 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SOX12 can be used in a range of immunoassay formats including, but not limited to, Dot Blot (DB), Immunocytochemistry (ICC), Western Blot (WB). Researchers should empirically determine the suitability of the SOX12 sox12 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SOX12, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
