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Testing Data

Mouse SNAT1 Monoclonal Antibody | anti-SNAT1 antibody

SNAT1 Neurotransmitter Transporter Monoclonal Antibody

Gene Names
SLC38A1; ATA1; NAT2; SAT1; SNAT1
Applications
Immunoblot, Western Blot, Immunohistochemistry
Synonyms
SNAT1; Monoclonal Antibody; SNAT1 Neurotransmitter Transporter Monoclonal Antibody; Anti-SNAT1 Neurotransmitter Transporter; anti-SNAT1 antibody
Ordering
For Research Use Only!
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Specificity
This antibody recognizes human, mouse, and rat SNAT1.
Sequence Length
503
Applicable Applications for anti-SNAT1 antibody
Immunoblot (IB), Immunohistochemistry (IHC)
Application Notes
Immunoblotting: Use at 1-2ug/ml. A band of ~50kDa is detected.
Immunohistochemistry: Use at 1-5ug/ml.
Antigen
Fusion protein corresponding to aa 1-63 (cytoplasmic N-terminus) of rat SNAT1 (accession no. NP_620187.1).
Positive Control
Rat neocortical neurons cultured under amino acid starvation conditions.
Dilution Instructions
Dilute in PBS or medium which is identical to that used in the assay system.
Preparation and Storage
This product is stable for at least 1 year at -20 degree C. Freeze in multiple aliquots to avoid repeated freeze-thaw cycles.

Testing Data

Testing Data
Related Product Information for anti-SNAT1 antibody
The sodium-coupled neutral amino acid transporters (SNAT) include System A subtypes SNAT1, SNAT2, and SNAT4 and System N subtypes SNAT3 and SNAT5. These transporters are essential for uptake of nutrients, energy production, metabolism, detoxification, and the cycling of neurotransmitters. SNAT1 is responsible for transport of glutamine and may be involved in the generation of glutamate in the retina. SNAT1 is found in heart, brain, and placenta, and expression levels are high in certain neuronal populations in the central nervous system.
Product Categories/Family for anti-SNAT1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
54,048 Da
NCBI Official Full Name
sodium-coupled neutral amino acid transporter 1 isoform 2
NCBI Official Synonym Full Names
solute carrier family 38 member 1
NCBI Official Symbol
SLC38A1
NCBI Official Synonym Symbols
ATA1; NAT2; SAT1; SNAT1
NCBI Protein Information
sodium-coupled neutral amino acid transporter 1
UniProt Protein Name
Sodium-coupled neutral amino acid transporter 1
UniProt Gene Name
SLC38A1
UniProt Synonym Gene Names
ATA1; NAT2; SAT1; SNAT1
UniProt Entry Name
S38A1_HUMAN

NCBI Description

Amino acid transporters play essential roles in the uptake of nutrients, production of energy, chemical metabolism, detoxification, and neurotransmitter cycling. SLC38A1 is an important transporter of glutamine, an intermediate in the detoxification of ammonia and the production of urea. Glutamine serves as a precursor for the synaptic transmitter, glutamate (Gu et al., 2001 [PubMed 11325958]).[supplied by OMIM, Mar 2008]

Uniprot Description

SLC38A1: Functions as a sodium-dependent amino acid transporter. Mediates the saturable, pH-sensitive and electrogenic cotransport of glutamine and sodium ions with a stoichiometry of 1:1. May also transport small zwitterionic and aliphatic amino acids with a lower affinity. May supply glutamatergic and GABAergic neurons with glutamine which is required for the synthesis of the neurotransmitters glutamate and GABA. Belongs to the amino acid/polyamine transporter 2 family.

Protein type: Transporter, SLC family; Membrane protein, integral; Membrane protein, multi-pass; Transporter

Chromosomal Location of Human Ortholog: 12q13.11

Cellular Component: integral to membrane; integral to plasma membrane; plasma membrane

Molecular Function: amino acid transmembrane transporter activity; L-amino acid transmembrane transporter activity; L-asparagine transmembrane transporter activity; L-glutamine transmembrane transporter activity; L-histidine transmembrane transporter activity; neutral amino acid transmembrane transporter activity; protein binding; sodium:amino acid symporter activity

Biological Process: amino acid transport; asparagine transport; glutamine transport; histidine transport; L-amino acid transport; neurotransmitter uptake; neutral amino acid transport; sodium ion transport

Research Articles on SNAT1

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Product Notes

The SNAT1 slc38a1 (Catalog #AAA190906) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's SNAT1 can be used in a range of immunoassay formats including, but not limited to, Immunoblot (IB), Immunohistochemistry (IHC). Immunoblotting: Use at 1-2ug/ml. A band of ~50kDa is detected. Immunohistochemistry: Use at 1-5ug/ml. Researchers should empirically determine the suitability of the SNAT1 slc38a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SNAT1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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