Typical Testing Data/Standard Curve (for reference only)
Human Sodium-Coupled Neutral Amino Acid Transporter 1 (SLC38A1) ELISA Kit | SLC38A1 elisa kit
Human Sodium-Coupled Neutral Amino Acid Transporter 1 (SLC38A1) ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Background/Introduction: Amino acid transporters play essential roles in the uptake of nutrients, production of energy, chemical metabolism, detoxification, and neurotransmitter cycling. SLC38A1 is an important transporter of glutamine, an intermediate in the detoxification of ammonia and the production of urea. Glutamine serves as a precursor for the synaptic transmitter, glutamate.
NCBI and Uniprot Product Information
NCBI Description
Amino acid transporters play essential roles in the uptake of nutrients, production of energy, chemical metabolism, detoxification, and neurotransmitter cycling. SLC38A1 is an important transporter of glutamine, an intermediate in the detoxification of ammonia and the production of urea. Glutamine serves as a precursor for the synaptic transmitter, glutamate (Gu et al., 2001 [PubMed 11325958]).[supplied by OMIM, Mar 2008]
Uniprot Description
SLC38A1: Functions as a sodium-dependent amino acid transporter. Mediates the saturable, pH-sensitive and electrogenic cotransport of glutamine and sodium ions with a stoichiometry of 1:1. May also transport small zwitterionic and aliphatic amino acids with a lower affinity. May supply glutamatergic and GABAergic neurons with glutamine which is required for the synthesis of the neurotransmitters glutamate and GABA. Belongs to the amino acid/polyamine transporter 2 family.
Protein type: Transporter, SLC family; Transporter; Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 12q13.11
Cellular Component: integral to plasma membrane; plasma membrane; integral to membrane
Molecular Function: neutral amino acid transmembrane transporter activity; sodium:amino acid symporter activity
Biological Process: neutral amino acid transport; synaptic transmission; amino acid transport; sodium ion transport; neurotransmitter uptake; ion transport; transmembrane transport
Research Articles on SLC38A1
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Product Notes
The Human SLC38A1 slc38a1 (Catalog #AAA9714268) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9714268 ELISA Kit recognizes Human SLC38A1. It is sometimes possible for the material contained within the vial of "Sodium-Coupled Neutral Amino Acid Transporter 1 (SLC38A1), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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