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Mouse SNAP alpha Monoclonal Antibody | anti-SNAP alpha antibody

SNAP alpha

Gene Names
NAPA; SNAPA
Reactivity
Human, Rat, Bovine
Applications
Western Blot, Immunoprecipitation
Synonyms
SNAP alpha; Monoclonal Antibody; alpha/beta SNAP; mouse anti alpha soluble NSF attachment protein; SNAPA; anti-SNAP alpha antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human, Rat, Bovine
Clonality
Monoclonal
Isotype
IgG1
Clone Number
4E4
Form/Format
Provided as sterile filtered solution containing 20 mM sodium phosphate, 150 mM sodium chloride, 50% glycerol at pH 7.5
Sequence Length
295
Applicable Applications for anti-SNAP alpha antibody
Western Blot (WB), Immunoprecipitation (IP)
Immunogen
Hybridoma produced by the fusion of splenocytes from mice immunized with recombinant human a-SNAP protein and mouse myeloma cells.
Positive Control
Rat Brain Lysate
Preparation and Storage
Product should be stored at -20 degree C. Aliquot to avoid freeze/thaw cycles
Related Product Information for anti-SNAP alpha antibody
SNAPs (soluble NSF attachment proteins), acting in concert SNAREs (SNAP receptors) and the N-ethylmaleimide-sensitive fusion protein (NSF), are required for the fusion of transport vesicles to their target membranes in synaptic transmission, intra-Golgi transport, endosome-to-endosome fusion and transcytotic vesicles-to-plasma membrane transport. Vesicle-to-target membrane docking (initial contact) occurs when the vesicle SNARE binds to its cognate target membrane SNARE. a-SNAP (or bSNAP in brain) then binds to this docking complex and mediates the binding of NSF and thus the formation of a 20 S fusion particle. It is thought that, once NSF is bound, ATP hydrolysis by NSF initiates the fusion process. Whereas a-SNAP is expressed in all mammalian tissues, b-SNAP is expressed only in brain.
Product Categories/Family for anti-SNAP alpha antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
36
NCBI Official Full Name
alpha-soluble NSF attachment protein
NCBI Official Synonym Full Names
N-ethylmaleimide-sensitive factor attachment protein, alpha
NCBI Official Symbol
NAPA
NCBI Official Synonym Symbols
SNAPA
NCBI Protein Information
alpha-soluble NSF attachment protein; alpha-SNAP
UniProt Protein Name
Alpha-soluble NSF attachment protein
UniProt Gene Name
NAPA
UniProt Synonym Gene Names
SNAPA; SNAP-alpha
UniProt Entry Name
SNAA_HUMAN

NCBI Description

This gene encodes a member of the soluble NSF attachment protein (SNAP) family. SNAP proteins play a critical role in the docking and fusion of vesicles to target membranes as part of the 20S NSF-SNAP-SNARE complex. The encoded protein plays a role in the completion of membrane fusion by mediating the interaction of N-ethylmaleimide-sensitive factor (NSF) with the vesicle-associated and membrane-associated SNAP receptor (SNARE) complex, and stimulating the ATPase activity of NSF. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jun 2011]

Uniprot Description

Function: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

Subunit structure: Interacts with PRKCABP, and disrupts the interaction between GRIA2 and PRKCABP, leading to the internalization of GRIA2. Found in a complex with VAMP8

By similarity. Component of a SNARE-like complex that contains at least ZW10, USE1L, RINT1, STX18 and NAPA/SNAP-alpha. Interacts with VTI1A. Interacts with STX12

By similarity. Ref.7

Subcellular location: Membrane; Peripheral membrane protein.

Sequence similarities: Belongs to the SNAP family.

Research Articles on SNAP alpha

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Product Notes

The SNAP alpha napa (Catalog #AAA395070) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The SNAP alpha reacts with Human, Rat, Bovine and may cross-react with other species as described in the data sheet. AAA Biotech's SNAP alpha can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the SNAP alpha napa for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SNAP alpha, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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