Western Blot (WB)
(Western Blot analysis of various cell lines using SLCO1B3 Monoclonal Antibody at dilution of 1:4000.)
Mouse anti-Human SLCO1B3 Monoclonal Antibody | anti-SLCO1B3 antibody
SLCO1B3 Monoclonal Antibody
Gene Names
SLCO1B3; LST3; HBLRR; LST-2; OATP8; OATP-8; OATP1B3; SLC21A8; LST-3TM13
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Protein G Purification
Synonyms
SLCO1B3; Monoclonal Antibody; SLCO1B3 Monoclonal Antibody; LST 2; LST 3TM13; LST2; LST3; OATP 8; OATP1B3; OATP8; Organic anion transporter 8; SLC21A8; anti-SLCO1B3 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
1D9A4
Purity/Purification
Protein G Purification
Sequence Length
1019
Applicable Applications for anti-SLCO1B3 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
WB: 1:1000-1:10000
IHC: 1:50-1:500
IHC: 1:50-1:500
Immunogen
Fusion Protein of SLCO1B3
Buffer
PBS with 0.02% sodium azide, 50% glycerol, PH7.3
Calculated MW
702aa;77kDa
Observed MW
68-77kDa
Preparation and Storage
Store at -20°C. Avoid freeze / thaw cycles.
Western Blot (WB)
(Western Blot analysis of various cell lines using SLCO1B3 Monoclonal Antibody at dilution of 1:4000.)
Western Blot (WB)
(Western Blot analysis of various cell lines using SLCO1B3 Monoclonal Antibody at dilution of 1:4000.)
Related Product Information for anti-SLCO1B3 antibody
SLCO1B3, also known as OATP8 or OATP1B3, is a member of Organic Anion Transporting Polypeptides (OATPs) which are sodium-independent organic anion transporters mediating the uptake of a wide range of structurally diverse endogenous and exogenous compoundsincluding bile acids, hormone conjugates, peptides, toxins, as well as a multitude of therapeutic drugs. SLCO1B3 is specifically expressed in liver under normal condition, while its expression has also been observed in cancer tissues like colon, prostate and pancreas. The molecular mass of SLCO1B3 is highly dependent on the glycosylation modification (deglycosylated form of 65 kDa, fully-glycosylated form of 120 kDa).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
Homo sapiens solute carrier organic anion transporter family, member 1B3, mRNA
NCBI Official Synonym Full Names
solute carrier organic anion transporter family member 1B3
NCBI Official Symbol
SLCO1B3
NCBI Official Synonym Symbols
LST3; HBLRR; LST-2; OATP8; OATP-8; OATP1B3; SLC21A8; LST-3TM13
NCBI Protein Information
solute carrier organic anion transporter family member 1B3
UniProt Protein Name
Solute carrier organic anion transporter family member
Protein Family
UniProt Gene Name
SLCO1B3
NCBI Description
This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of endogenous and xenobiotic compounds and plays a critical role in bile acid and bilirubin transport. Mutations in this gene are a cause of Rotor type hyperbilirubinemia. Alternative splicing of this gene and the use of alternative promoters results in transcript variants encoding different isoforms that differ in their tissue specificity. [provided by RefSeq, Mar 2017]
Research Articles on SLCO1B3
Similar Products
Product Notes
The SLCO1B3 slco1b3 (Catalog #AAA2549138) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The SLCO1B3 Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SLCO1B3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA). WB: 1:1000-1:10000 IHC: 1:50-1:500. Researchers should empirically determine the suitability of the SLCO1B3 slco1b3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLCO1B3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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