Western Blot (WB)
(SLC22A8 monoclonal antibody Western Blot analysis of SLC22A8 expression in rat muscle.)
Mouse anti-Human, Rat SLC22A8 Monoclonal Antibody | anti-SLC22A8 antibody
SLC22A8 (Solute Carrier Family 22 Member 8, Organic Anion Transporter 3, OAT3, hOAT3)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Western Blot (WB)
(SLC22A8 monoclonal antibody Western Blot analysis of SLC22A8 expression in rat muscle.)
Western Blot (WB)
(SLC22A8 monoclonal antibody Western Blot analysis of SLC22A8 expression in rat muscle.)
Testing Data
(Detection limit for recombinant GST tagged SLC22A8 is 0.3ng/ml as a capture antibody.)
Testing Data
(Detection limit for recombinant GST tagged SLC22A8 is 0.3ng/ml as a capture antibody.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and appears to be localized to the basolateral membrane of the kidney. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, May 2010]
Uniprot Description
SLC22A8: Plays an important role in the excretion/detoxification of endogenous and exogenous organic anions, especially from the brain and kidney. Involved in the transport basolateral of steviol, fexofenadine. Transports benzylpenicillin (PCG), estrone- 3-sulfate (E1S), cimetidine (CMD), 2,4-dichloro-phenoxyacetate (2,4-D), p-amino-hippurate (PAH), acyclovir (ACV) and ochratoxin (OTA). Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Transporter; Transporter, SLC family; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 11q11
Cellular Component: basolateral plasma membrane; integral to membrane; plasma membrane
Molecular Function: protein kinase C binding; inorganic anion exchanger activity; organic anion transmembrane transporter activity; quaternary ammonium group transmembrane transporter activity
Biological Process: quaternary ammonium group transport; response to toxin; response to methotrexate; transmembrane transport
Research Articles on SLC22A8
Similar Products
Product Notes
The SLC22A8 slc22a8 (Catalog #AAA6009429) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The SLC22A8 (Solute Carrier Family 22 Member 8, Organic Anion Transporter 3, OAT3, hOAT3) reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SLC22A8 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA). Suitable for use in ELISA. Researchers should empirically determine the suitability of the SLC22A8 slc22a8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: TPESIRWLVL SGKSSKALKI LRRVAVFNGK KEEGERLSLE ELKLNLQKEI SLAKAKYTAS DLFRIPMLRR. It is sometimes possible for the material contained within the vial of "SLC22A8, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
