Mouse anti-Human Serotonin Receptor 1B Monoclonal Antibody | anti-HTR1B antibody
Serotonin Receptor 1B (5-Hydroxytryptamine (Serotonin) Receptor 1B, 5-Hydroxytryptamine Receptor 1B, 5-HT-1B, 5-HT-1D-beta, 5-HT1B, 5-HT1B Receptor, 5-HT1DB, HTR1B, HTR1D2, HTR1DB, S12, Serotonin 1D beta Receptor)
Reactivity
Human
Applications
Immunohistochemistry
Purity
Affinity PurifiedPurified by Protein G affinity chromatography.
Synonyms
Serotonin Receptor 1B; Monoclonal Antibody; Serotonin Receptor 1B (5-Hydroxytryptamine (Serotonin) Receptor 1B; 5-Hydroxytryptamine Receptor 1B; 5-HT-1B; 5-HT-1D-beta; 5-HT1B; 5-HT1B Receptor; 5-HT1DB; HTR1B; HTR1D2; HTR1DB; S12; Serotonin 1D beta Receptor); Anti -Serotonin Receptor 1B (5-Hydroxytryptamine (Serotonin) Receptor 1B; anti-HTR1B antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
9i139
Specificity
Recognizes human Serotonin Receptor 1B. Species Sequence Homology: mouse and rat; 92%.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Purified by Protein G affinity chromatography.
Form/Format
Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 200ul sterile PBS.
Applicable Applications for anti-HTR1B antibody
Immunohistochemistry (IHC)
Application Notes
Suitable for use in Immunohistochemistry.
Dilution: Immunohistochemistry (Paraffin): 25ug/ml detected Serotonin Receptor 1B in normal human brain cortex and glia tissue sections.
Dilution: Immunohistochemistry (Paraffin): 25ug/ml detected Serotonin Receptor 1B in normal human brain cortex and glia tissue sections.
Immunogen
Purified human Serotonin Receptor 1B transfected NS0 cells (Accession #P28222).
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-HTR1B antibody
5-HT1B is a 7TM receptor for serotonin and is expressed on striatal neurons and Purkinje cells in the cerebellum. 5HT1B ligation inhibits glycinergic signaling, appetite, circadian rhythm light responsiveness, and trigeminal-mediated nociception. It is an important pharmacologic target in the treatment of migrane headaches. Human 5HT1B shares 92% aa sequence identity with mouse and rat 5HT1B.
Product Categories/Family for anti-HTR1B antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
42,930 Da
NCBI Official Full Name
serotonin receptor 1B
NCBI Official Symbol
HTR1B
NCBI Protein Information
5-hydroxytryptamine receptor 1B; 5-HT1B; 5-HT-1B; 5-HTR1B; 5-HT1D beta; 5-HT1D subtype beta; serotonin receptor 1B; 5-Hydroxytryptamine 1D receptor subtype beta
UniProt Protein Name
5-hydroxytryptamine receptor 1B
Protein Family
UniProt Gene Name
HTR1B
UniProt Entry Name
5HT1B_CANFA
Uniprot Description
Function: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Post-translational modification: Phosphorylated
By similarity.Palmitoylated
Sequence similarities: Belongs to the G-protein coupled receptor 1 family.
Research Articles on HTR1B
Similar Products
Product Notes
The HTR1B htr1b (Catalog #AAA608018) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Serotonin Receptor 1B (5-Hydroxytryptamine (Serotonin) Receptor 1B, 5-Hydroxytryptamine Receptor 1B, 5-HT-1B, 5-HT-1D-beta, 5-HT1B, 5-HT1B Receptor, 5-HT1DB, HTR1B, HTR1D2, HTR1DB, S12, Serotonin 1D beta Receptor) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Serotonin Receptor 1B can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Suitable for use in Immunohistochemistry. Dilution: Immunohistochemistry (Paraffin): 25ug/ml detected Serotonin Receptor 1B in normal human brain cortex and glia tissue sections. Researchers should empirically determine the suitability of the HTR1B htr1b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Serotonin Receptor 1B, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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