Mouse anti-Human, Mouse SEPT2 Monoclonal Antibody | anti-SEPT2 antibody

SEPT2 Mouse Monoclonal

Cat. Num. AAA7603955

• Gene Names: SEPT2; DIFF6; NEDD5; NEDD-5; Pnutl3; hNedd5
• Reactivity: Human, Mouse
• Applications: ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
• Purity: >=95% as determined by SDS-PAGE; Protein A+G purification
• Synonyms: SEPT2; Monoclonal Antibody; SEPT2 Mouse Monoclonal; anti-SEPT2 antibody

• Host: Mouse
• Reactivity: Human, Mouse
• Clonality: Monoclonal
• Isotype: IgG1
• Purity/Purification: >=95% as determined by SDS-PAGE; Protein A+G purification
• Form/Format: Liquid
• Sequence Length: 361

• Applicable Applications for anti-SEPT2 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
• Immunogen: Septin 2
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using MBS7603955 (SEPT2 Antibody) at dilution of 1:800)

Immunofluorescence (IF)

(Immunofluorescence analysis of U2OS cells using SEPT2 antibody (MBS7603955) . Blue: DAPI for nuclear staining.)

Western Blot (WB)

(HEK-293 cells were subjected to SDS PAGE followed by western blot with MBS7603955 (SEPT2 Antibody) at various dilutions.)

NCBI and Uniprot Product Information

• NCBI GI #: 1005261192
• NCBI GeneID: 4735
• NCBI Accession #: NP_001307960.1
• NCBI GenBank Nucleotide #: NM_001321031.1
• Molecular Weight: 42,685 Da
• NCBI Official Full Name: septin-2 isoform a
• NCBI Official Synonym Full Names: septin 2
• NCBI Official Symbol: SEPT2
• NCBI Official Synonym Symbols: DIFF6; NEDD5; NEDD-5; Pnutl3; hNedd5
• NCBI Protein Information: septin-2
• UniProt Protein Name: Septin-2
• UniProt Gene Name: SEPT2
• UniProt Synonym Gene Names: DIFF6; KIAA0158; NEDD5; NEDD-5
• UniProt Entry Name: SEPT2_HUMAN

Uniprot Description

SEPT2: a member of the septin family of proteins. May be involved in the process of cytokinesis. Accumulates near the contractile ring from anaphase through telophase, and finally condenses into the midbody. In interphase and postmitotic cells, localized to fibrous or granular structures, depending on the growth state of the cell.

Protein type: Cytoskeletal; Motility/polarity/chemotaxis; Hydrolase; Cell cycle regulation; Cell development/differentiation

Chromosomal Location of Human Ortholog: 2q37

Cellular Component: actin cytoskeleton; axoneme; cell cortex; cleavage furrow; cytoplasm; exocyst; midbody; myelin sheath; nonmotile primary cilium; nucleolus; nucleus; perinuclear region of cytoplasm; photoreceptor connecting cilium; spindle; synapse

Molecular Function: enzyme regulator activity; GTP binding; protein binding; protein complex scaffold

Biological Process: cell division; cilium biogenesis; mitosis; neurite development; regulation of catalytic activity; regulation of L-glutamate transport; regulation of protein localization; smoothened signaling pathway