Testing Data
(Detection of mouse Semaphorin 4D with MBS605771. Lysates were prepared from mouse brain or thymus extract in reducing (R) or non-reducing (NR) sample buffer, resolved by SDS-PAGE (30ug total protein/lane), and transferred to an Immobilon-P membrane. The blot was developed with 2ug/ml MBS605771.)
Rat anti-Mouse Semaphorin 4D Monoclonal Antibody | anti-SEMA4D antibody
Semaphorin 4D (BB18, A8, GR3, CD100 antigen, SEMA4D, CD100, SEMAJ)
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Dilution: Western Blot: 2ug/ml
ELISA: 0.5-1ug/ml
Testing Data
(Detection of mouse Semaphorin 4D with MBS605771. Lysates were prepared from mouse brain or thymus extract in reducing (R) or non-reducing (NR) sample buffer, resolved by SDS-PAGE (30ug total protein/lane), and transferred to an Immobilon-P membrane. The blot was developed with 2ug/ml MBS605771.)
Testing Data
(Detection of mouse Semaphorin 4D with MBS605771. Lysates were prepared from mouse brain or thymus extract in reducing (R) or non-reducing (NR) sample buffer, resolved by SDS-PAGE (30ug total protein/lane), and transferred to an Immobilon-P membrane. The blot was developed with 2ug/ml MBS605771.)
NCBI and Uniprot Product Information
Uniprot Description
SEMA4D: a single-pass type I membrane protein that my play a functional role in the immune system, as well as in the nervous system. Induces B-cells to aggregate and improves their viability in vitro.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 9q22.2
Cellular Component: extracellular space; integral to plasma membrane; plasma membrane
Molecular Function: protein binding; transmembrane receptor activity; receptor activity; semaphorin receptor binding; receptor binding
Biological Process: axon guidance; negative regulation of peptidyl-tyrosine phosphorylation; regulation of dendrite morphogenesis; negative regulation of transcription from RNA polymerase II promoter; negative regulation of cell adhesion; positive regulation of phosphoinositide 3-kinase cascade; regulation of cell shape; positive regulation of peptidyl-tyrosine phosphorylation; negative regulation of osteoblast differentiation; immune response; positive regulation of protein amino acid phosphorylation; cell adhesion; positive regulation of collateral sprouting; positive regulation of cell migration; negative regulation of apoptosis; regulation of cell projection organization and biogenesis
Research Articles on SEMA4D
Similar Products
Product Notes
The SEMA4D sema4d (Catalog #AAA605771) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The Semaphorin 4D (BB18, A8, GR3, CD100 antigen, SEMA4D, CD100, SEMAJ) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Semaphorin 4D can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in ELISA and Western Blot. Dilution: Western Blot: 2ug/ml ELISA: 0.5-1ug/ml. Researchers should empirically determine the suitability of the SEMA4D sema4d for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Semaphorin 4D, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
