Western Blot (WB)
(Western Blot detection against Immunogen (37.66kD).)
Mouse anti-Human RALGPS2 Monoclonal Antibody | anti-RALGPS2 antibody
RALGPS2 (Ras-specific Guanine Nucleotide-releasing Factor RalGPS2, RalA Exchange Factor RalGPS2, Ral GEF with PH Domain and SH3-binding Motif 2, FLJ10244, FLJ25604)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Dilution: Immunofluorescence: 10ug/ml
Western Blot (WB)
(Western Blot detection against Immunogen (37.66kD).)
Western Blot (WB)
(Western Blot detection against Immunogen (37.66kD).)
Western Blot (WB)
(RALGPS2 monoclonal antibody, Western Blot analysis of RALGPS2 expression in HeLa.)
Western Blot (WB)
(RALGPS2 monoclonal antibody, Western Blot analysis of RALGPS2 expression in HeLa.)
Immunofluorescence (IF)
(Immunofluorescence of monoclonal antibody to RALGPS2 on HeLa cell. [antibody concentration 10ug/ml].)
Immunofluorescence (IF)
(Immunofluorescence of monoclonal antibody to RALGPS2 on HeLa cell. [antibody concentration 10ug/ml].)
Testing Data
(Detection limit for recombinant GST tagged RALGPS2 is ~0.03ng/ml as a capture antibody.)
Testing Data
(Detection limit for recombinant GST tagged RALGPS2 is ~0.03ng/ml as a capture antibody.)
NCBI and Uniprot Product Information
Uniprot Description
Function: Guanine nucleotide exchange factor for the small GTPase RALA. May be involved in cytoskeletal organization. May also be involved in the stimulation of transcription in a Ras-independent fashion
By similarity.
Subunit structure: Interacts with the SH3 domains of GRB2 and PLCG1
By similarity. Interacts with RALA
By similarity.
Subcellular location: Cytoplasm
By similarity. Cell membrane
By similarity. Note: Associates with membranes through the PH domain
By similarity.
Domain: The PH domain mediates binding to phosphatidylinositol 4,5-bisphosphate
By similarity.
Involvement in disease: RALGPS2 is a potential candidate gene for susceptibility to Alzheimer disease linked to 1q24. Ref.5
Sequence similarities: Contains 1 PH domain.Contains 1 Ras-GEF domain.
Sequence caution: The sequence CAH71098.1 differs from that shown. Reason: Erroneous gene model prediction. The sequence CAI21919.1 differs from that shown. Reason: Erroneous gene model prediction. The sequence CAI21925.1 differs from that shown. Reason: Erroneous gene model prediction.
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Product Notes
The RALGPS2 ralgps2 (Catalog #AAA648486) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The RALGPS2 (Ras-specific Guanine Nucleotide-releasing Factor RalGPS2, RalA Exchange Factor RalGPS2, Ral GEF with PH Domain and SH3-binding Motif 2, FLJ10244, FLJ25604) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RALGPS2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunofluorescence (IF). Suitable for use in Immunofluorescence, ELISA and Western Blot. Dilution: Immunofluorescence: 10ug/ml. Researchers should empirically determine the suitability of the RALGPS2 ralgps2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: LKIEPGTSTP RSAASREDLV GPEVGASPQS GRKSVAAEGA LLPQTPPSPR NLIPHGHRKC HSLGYNFIHK MNTAEFKSAT FPNAGPRHLL DDSVMEPHAP SRGQA. It is sometimes possible for the material contained within the vial of "RALGPS2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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