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Rat Rab11B Monoclonal Antibody | anti-Rab11B antibody

Rab11B antibody

Gene Names
RAB11B; H-YPT3
Applications
Immunofluorescence, Western Blot
Purity
Rab11B antibody was purified by Protein G chromatography.
Synonyms
Rab11B; Monoclonal Antibody; Rab11B antibody; Monoclonal Rab11B; Anti-Rab11B; RabB-11; RabB 11; Rab-11B; Rab 11B; anti-Rab11B antibody
Ordering
For Research Use Only!
Host
Rat
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
KT80
Specificity
Mouse
Purity/Purification
Rab11B antibody was purified by Protein G chromatography.
Form/Format
Supplied in PBS containing 0.1% sodium azide as a preservative
Concentration
1 mg/ml (varies by lot)
Sequence Length
218
Applicable Applications for anti-Rab11B antibody
Immunofluorescence (IF), Western Blot (WB)
Application Notes
IF: 10 ug/ml
WB: 1 ug/ml
Biological Significance
The Ras superfamily of small GTP-binding proteins, which includes the Ras, Ral, Rho, Rap, and Rab families, is involved in controlling a diverse set of essential cellular functions. The Rab family, including RAB11B, appears to play a critical role in regulating exocytotic and endocytotic pathways.
Biohazard Information
This product contains sodium azide which is hazardous
Immunogen
Rab11B antibody was raised in Rat using Mouse RAB11B and GST fusion protein as the immunogen.
Preparation and Storage
Store at 4 degree C for up to 1 month. For long term storage, aliquot and store at -20 to -80 degree C. Avoid repeated freeze/thaw cycles.
Related Product Information for anti-Rab11B antibody
Rat monoclonal Rab11B antibody
Product Categories/Family for anti-Rab11B antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
19,971 Da
NCBI Official Full Name
RAB11B, partial
NCBI Official Synonym Full Names
RAB11B, member RAS oncogene family
NCBI Official Symbol
RAB11B
NCBI Official Synonym Symbols
H-YPT3
NCBI Protein Information
ras-related protein Rab-11B
UniProt Protein Name
Ras-related protein Rab-11B
Protein Family
UniProt Gene Name
RAB11B
UniProt Synonym Gene Names
YPT3
UniProt Entry Name
RB11B_HUMAN

NCBI Description

The Ras superfamily of small GTP-binding proteins, which includes the Ras (see MIM 190020), Ral (see MIM 179550), Rho (see MIM 165390), Rap (see MIM 179520), and Rab (see MIM 179508) families, is involved in controlling a diverse set of essential cellular functions. The Rab family, including RAB11B, appears to play a critical role in regulating exocytotic and endocytotic pathways (summary by Zhu et al., 1994 [PubMed 7811277]).[supplied by OMIM, Nov 2010]

Uniprot Description

RAB11B: GTPase that modulates endosomal trafficking. Acts as a major regulator of membrane delivery during cytokinesis. Interacts with RAB11FIP1, RAB11FIP2, RAB11FIP3 and RAB11FIP4. Belongs to the small GTPase superfamily. Rab family.

Protein type: G protein, monomeric; G protein, monomeric, Rab; G protein

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: phagocytic vesicle membrane; synaptic vesicle; recycling endosome; synaptic vesicle membrane; mitochondrion; recycling endosome membrane; phagocytic vesicle; cell junction

Molecular Function: GTPase activity; protein binding; GDP binding; GTP binding; myosin V binding

Biological Process: receptor recycling; intracellular protein transport; regulated secretory pathway; constitutive secretory pathway; transferrin transport; Rab protein signal transduction; melanosome transport

Research Articles on Rab11B

Similar Products

Product Notes

The Rab11B rab11b (Catalog #AAA830032) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Rab11B can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF), Western Blot (WB). IF: 10 ug/ml WB: 1 ug/ml. Researchers should empirically determine the suitability of the Rab11B rab11b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Rab11B, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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