Immunofluorescence (IF)
(Immunofluorescent staining of COS7 cells transiently transfected with recombinant PTPRE protein using PTPRE antibody)
Mouse PTPRE Monoclonal Antibody | anti-PTPRE antibody
PTPRE antibody
IHC: 1:50
WB: 1:1000
Immunofluorescence (IF)
(Immunofluorescent staining of COS7 cells transiently transfected with recombinant PTPRE protein using PTPRE antibody)
Immunofluorescence (IF)
(Immunofluorescent staining of COS7 cells transiently transfected with recombinant PTPRE protein using PTPRE antibody)
Western Blot (WB)
(Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant PTPRE protein (Right) or empty vector (Left) detected with PTPRE antibody)
Western Blot (WB)
(Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant PTPRE protein (Right) or empty vector (Left) detected with PTPRE antibody)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of PTPRE protein in paraffin embedded Adenocarcinoma of Human colon tissue using PTPRE antibody)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of PTPRE protein in paraffin embedded Adenocarcinoma of Human colon tissue using PTPRE antibody)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants of this gene have been reported, one of which encodes a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; Another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokines induced SATA signaling, as well as the activation of voltage-gated K+ channels. [provided by RefSeq, Jul 2008]
Uniprot Description
PTPRE: a cytoplasmic and transmembrane receptor protein tyrosine phosphatase that regulates IL-10 and TNFA biosynthesis, myelination and cell-matrix adhesion, overexpression reduces tumor development
Protein type: Membrane protein, integral; Motility/polarity/chemotaxis; Receptor protein phosphatase, tyrosine; EC 3.1.3.48
Chromosomal Location of Human Ortholog: 10q26
Cellular Component: cytoplasm; integral to membrane; plasma membrane; nucleus
Molecular Function: protein binding; protein homodimerization activity; transmembrane receptor protein tyrosine phosphatase activity
Biological Process: negative regulation of insulin receptor signaling pathway; protein amino acid dephosphorylation; transmembrane receptor protein tyrosine phosphatase signaling pathway; regulation of mast cell activation
Research Articles on PTPRE
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Product Notes
The PTPRE ptpre (Catalog #AAA833554) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's PTPRE can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB). IF: 1:100 IHC: 1:50 WB: 1:1000. Researchers should empirically determine the suitability of the PTPRE ptpre for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PTPRE, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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