Structure
Phlorizin Biochemical
Phlorizin
Purity
>=98%
Synonyms
Phlorizin; 1-?[2-?(beta-?D-?glucopyranosyloxy)-?4; ?6-?dihydroxyphenyl]-?3-?(4-?hydroxyphenyl)-?1-?propanone; NSC 2833; Florizidin; Phlorizin biochemical
Purity/Purification
>=98%
Form/Format
Appearance: White to yellow solid
CAS Number
60-81-1
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
No
MDL Number
MFCD00149438
PubChem CID
6072
Solubility/Reconstitution Instructions
DMSO (~30 mg/ml) or EtOH (~ 5 mg/ml)
SMILES
C1=CC(=CC=C1CCC(=O)C2=C(C=C(C=C2OC3C(C(C(C(O3)CO)O)O)O)O)O)O
InChi
InChI=1S/C21H24O10/c22-9-16-18(27)19(28)20(29)21(31-16)30-15-8-12(24)7-14(26)17(15)13(25)6-3-10-1-4-11(23)5-2-10/h1-2,4-5,7-8,16,18-24,26-29H,3,6,9H2/t16-,18-,19+,20-,21-/m1/s1
InChi Key
IOUVKUPGCMBWBT-QNDFHXLGSA-N
Handling
Protect from light and air
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Shelf Life: 36 months
Structure
Structure
Related Product Information for Phlorizin biochemical
Background: Phlorizin is a competitive inhibitor of SGLT1 (sodium glucose co-transporter 1) and SGLT2 (sodium glucose co-transporter 2); this reduces renal glucose transport, lowering the amount of glucose in the blood. It competitively inhibits the initial rate of alpha-methyl-D-glucopyranoside (alpha-MDG) uptake in human COS-1 cells expressing hSGLT1 and hSGLT2 with IC?? values of 400 and 65 nM, respectively. In HEK293T cells expressing human SGLT1 and SGLT2, phlorizin exhibits Ki values of 140 and 11 nM, respectively, at 37 degree C.
Product Categories/Family for Phlorizin biochemical
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Product Notes
The Phlorizin (Catalog #AAA843268) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Phlorizin, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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