Testing Data
(1:2000 dilution of this antibody detected PPP4C on 40ug of cell lysates)
Mouse Protein Phosphatase 4C Monoclonal Antibody | anti-PPP4C antibody
Protein Phosphatase 4C Monoclonal Antibody
Gene Names
PPP4C; PP4; PPX; PP-X; PP4C; PPH3; PPP4
Reactivity
Human, Dog, Mouse, Bovine, Rat
Applications
Western Blot, Immunocytochemistry, Immunohistochemistry
Purity
Purified by antigen-affinity chromatography.
Synonyms
Protein Phosphatase 4C; Monoclonal Antibody; Protein Phosphatase 4C Monoclonal Antibody; serine/threonine-protein phosphatase 4 catalytic subunit PP-X protein phosphatase X; catalytic subunit protein phosphatase 4 (formerly X); catalytic subunit; anti-PPP4C antibody
Host
Mouse
Reactivity
Human, Dog, Mouse, Bovine, Rat
Clonality
Monoclonal
Isotype
IgG2a
Purity/Purification
Purified by antigen-affinity chromatography.
Form/Format
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Sequence Length
307
Applicable Applications for anti-PPP4C antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC)
Application Notes
Western blotting: 1:1000
Immunogen Type
Recombinant protein
Immunogen Description
Recombinant full length protein (307aa) of human PPP4C.
Target Name
Protein Phosphatase 4C
Preparation and Storage
store at -20 degree C
Testing Data
(1:2000 dilution of this antibody detected PPP4C on 40ug of cell lysates)
Testing Data
(1:2000 dilution of this antibody detected PPP4C on 40ug of cell lysates)
Testing Data
(HeLa cells using anti- PPP4C antibody diluted 1:200)
Testing Data
(HeLa cells using anti- PPP4C antibody diluted 1:200)
Immunohistochemistry (IHC)
(Paraffin-embedded human breast cancer using anti- PPP4C diluted 1:50-1:100)
Immunohistochemistry (IHC)
(Paraffin-embedded human breast cancer using anti- PPP4C diluted 1:50-1:100)
Product Categories/Family for anti-PPP4C antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
35,080 Da
NCBI Official Full Name
serine/threonine-protein phosphatase 4 catalytic subunit isoform 1
NCBI Official Synonym Full Names
protein phosphatase 4, catalytic subunit
NCBI Official Symbol
PPP4C
NCBI Official Synonym Symbols
PP4; PPX; PP-X; PP4C; PPH3; PPP4
NCBI Protein Information
serine/threonine-protein phosphatase 4 catalytic subunit
UniProt Protein Name
Serine/threonine-protein phosphatase 4 catalytic subunit
UniProt Gene Name
PPP4C
UniProt Synonym Gene Names
PPP4; PPX; PP4C; Pp4; PP-X
UniProt Entry Name
PP4C_HUMAN
Uniprot Description
PPP4C: a Ser/Thr phosphatase. A positive regulator of HPK1 and the HPK1-JNK signaling pathway. Mediates TNF-alpha-induced degradation of IRS-4 and plays a role in NF-kappaB p65 Thr dephosphorylation. Holoenzyme consists at least of a catalytic subunit PPP4C and a regulatory subunit PPP4R1.
Protein type: EC 3.1.3.16; Protein phosphatase, Ser/Thr (non-receptor)
Chromosomal Location of Human Ortholog: 16p11.2
Cellular Component: nucleoplasm; cytoplasm; plasma membrane; microtubule organizing center; nucleus
Molecular Function: NF-kappaB-inducing kinase activity; protein binding; metal ion binding; protein serine/threonine phosphatase activity
Biological Process: dephosphorylation
Research Articles on PPP4C
Similar Products
Product Notes
The PPP4C ppp4c (Catalog #AAA9400087) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Protein Phosphatase 4C Monoclonal Antibody reacts with Human, Dog, Mouse, Bovine, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Protein Phosphatase 4C can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC). Western blotting: 1:1000. Researchers should empirically determine the suitability of the PPP4C ppp4c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Protein Phosphatase 4C, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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