Mouse anti-Human PRDM1/BLIMP1 Monoclonal Antibody | anti-PRDM1/BLIMP1 antibody
PRDM1/BLIMP1 antibody (mAb)(Clone ROS195)
Gene Names
PRDM1; BLIMP1; PRDI-BF1
Reactivity
Human
Applications
Immunohistochemistry, Immunoprecipitation, Western Blot
Purity
Protein G Chromatography
Synonyms
PRDM1/BLIMP1; Monoclonal Antibody; PRDM1/BLIMP1 antibody (mAb)(Clone ROS195); PRDI-BF1; anti-PRDM1/BLIMP1 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
ROS195
Purity/Purification
Protein G Chromatography
Form/Format
Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic.
Concentration
1ug/ul (varies by lot)
Applicable Applications for anti-PRDM1/BLIMP1 antibody
Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
Immunogen
This PRDM1/BLIMP1 antibody was raised against full-length recombinant human PRDM1/BLIMP1 protein.
Preparation and Storage
Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20 degree C for up to 2 years. Keep all reagents on ice when not in storage.1ug/ul
Related Product Information for anti-PRDM1/BLIMP1 antibody
Short Description: Our PRDM1/BLIMP1 antibody (mAb)(Clone ROS195) was raised in a Mouse host. It has been validated for use in Immunohistochemistry, Immunoprecipitation and Western blot; it has been shown to react with Human samples.
Background: PRDM1/BLIMP1 is a transcriptional repressor that binds to specific target sites in DNA and recruits co-repressors. PRDM1/BLIMP1 is a master regulator for B cell terminal differentiation, is essential for normal development and immunity and a putative tumor suppressor in diffuse large B cell lymphomas (DLBCLs). PRDM1/BLIMP1 specifies primordial germ cells through the silencing of the default somatic pathway. PRDM1/BLIMP1 also acts as a master regulator of intestinal maturation.
Background: PRDM1/BLIMP1 is a transcriptional repressor that binds to specific target sites in DNA and recruits co-repressors. PRDM1/BLIMP1 is a master regulator for B cell terminal differentiation, is essential for normal development and immunity and a putative tumor suppressor in diffuse large B cell lymphomas (DLBCLs). PRDM1/BLIMP1 specifies primordial germ cells through the silencing of the default somatic pathway. PRDM1/BLIMP1 also acts as a master regulator of intestinal maturation.
Product Categories/Family for anti-PRDM1/BLIMP1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
76,835 Da
NCBI Official Full Name
PR domain zinc finger protein 1 isoform 1
NCBI Official Synonym Full Names
PR domain containing 1, with ZNF domain
NCBI Official Symbol
PRDM1
NCBI Official Synonym Symbols
BLIMP1; PRDI-BF1
NCBI Protein Information
PR domain zinc finger protein 1; BLIMP-1; PRDI-binding factor-1; B-lymphocyte-induced maturation protein 1; beta-interferon gene positive-regulatory domain I binding factor
UniProt Protein Name
PR domain zinc finger protein 1
UniProt Gene Name
PRDM1
UniProt Synonym Gene Names
BLIMP1; PRDI-BF1
UniProt Entry Name
PRDM1_HUMAN
NCBI Description
This gene encodes a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported. [provided by RefSeq, Jul 2008]
Research Articles on PRDM1/BLIMP1
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Product Notes
The PRDM1/BLIMP1 prdm1 (Catalog #AAA388791) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The PRDM1/BLIMP1 antibody (mAb)(Clone ROS195) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PRDM1/BLIMP1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB). Researchers should empirically determine the suitability of the PRDM1/BLIMP1 prdm1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PRDM1/BLIMP1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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