Immunohistochemistry (IHC)
(Anti-Pleckstrin antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Mouse anti-Human PLEK / Pleckstrin Monoclonal Antibody | anti-PLEK antibody
Mouse Monoclonal [clone 6E3] (IgG2a,k) to Human PLEK / Pleckstrin
Usage: Western Blot (Cell lysate) - positive control HeLa. Sandwich ELISA (Recombinant protein).
Immunohistochemistry (IHC)
(Anti-Pleckstrin antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Immunohistochemistry (IHC)
(Anti-Pleckstrin antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Immunohistochemistry (IHC)
(Anti-Pleckstrin antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Immunohistochemistry (IHC)
(Anti-Pleckstrin antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Immunohistochemistry (IHC)
(Anti-Pleckstrin antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Immunohistochemistry (IHC)
(Anti-Pleckstrin antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Western Blot (WB)
(PLEK monoclonal antibody clone 6E3 Western blot of PLEK expression in HeLa.)
Western Blot (WB)
(PLEK monoclonal antibody clone 6E3 Western blot of PLEK expression in HeLa.)
ELISA (EIA)
(Detection limit for recombinant GST tagged PLEK is approximately 0.3 ng/ml as a capture antibody.)
ELISA (EIA)
(Detection limit for recombinant GST tagged PLEK is approximately 0.3 ng/ml as a capture antibody.)
NCBI and Uniprot Product Information
Uniprot Description
pleckstrin: Major protein kinase C substrate of platelets.
Protein type: Lipid-binding
Chromosomal Location of Human Ortholog: 2p13.3
Cellular Component: membrane; cytoplasm; extracellular region; cytosol
Molecular Function: protein binding; protein homodimerization activity; protein kinase C binding; phosphatidylinositol-3,4-bisphosphate binding
Biological Process: negative regulation of calcium-mediated signaling; integrin-mediated signaling pathway; phospholipase C inhibition; platelet activation; positive regulation of actin filament depolymerization; negative regulation of G-protein coupled receptor protein signaling pathway; positive regulation of integrin activation; platelet degranulation; cell projection organization and biogenesis; actin cytoskeleton reorganization; ruffle organization and biogenesis; positive regulation of actin filament bundle formation; hemopoietic progenitor cell differentiation; phosphatidylinositol metabolic process; cortical actin cytoskeleton organization and biogenesis; blood coagulation; vesicle docking during exocytosis
Research Articles on PLEK
Similar Products
Product Notes
The PLEK plek (Catalog #AAA245747) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Monoclonal [clone 6E3] (IgG2a,k) to Human PLEK / Pleckstrin reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PLEK / Pleckstrin can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA). ELISA, IHC-P (5 ug/ml), WB (1:500 - 1:1000) Usage: Western Blot (Cell lysate) - positive control HeLa. Sandwich ELISA (Recombinant protein). Researchers should empirically determine the suitability of the PLEK plek for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PLEK / Pleckstrin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
